Crystal Structure, Hirshfeld Surface Analysis, and Computational Study of Quinolin-8-yl 4-Chlorobenzoate: Insights from Spectroscopic, Thermal, and Antitumor Properties

Crystal Structure, Hirshfeld Surface Analysis, and Computational Study of Quinolin-8-yl 4-Chlorobenzoate: Insights from Spectroscopic, Thermal, and Antitumor Properties

We report the time-efficient synthesis of quinolin-8-yl 4-chlorobenzoate (<b>3</b>) via an <i>O</i>-acylation reaction between 8-hydroxyquinoline (<b>1</b>) and 4-chlorobenzoyl chloride (<b>2</b>) mediated by triethylamine in acetonitrile under heating...

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Bibliographic Details
Main Authors:	Juan-Carlos Castillo, Diana Becerra, Mario A. Macías
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Crystals
Subjects:	8-hydroxyquinoline X-ray crystallography Hirshfeld surface maps molecular orbitals cancer
Online Access:	https://www.mdpi.com/2073-4352/13/4/694

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