Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy
We investigated the effect of lockdown measures implemented in Lombardy on selected obstetric and perinatal outcomes. Births that occurred during the two lockdowns imposed (i.e., the first from 16 March to 2 June 2020 and the second from 3 November 2020 to 5 April 2021) and the comparison periods (i...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/3/499 |
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| author | Giovanna Esposito Marta Rossi Alessandro Favilli Matteo Franchi Giovanni Corrao Fabio Parazzini Carlo La Vecchia |
| author_facet | Giovanna Esposito Marta Rossi Alessandro Favilli Matteo Franchi Giovanni Corrao Fabio Parazzini Carlo La Vecchia |
| author_sort | Giovanna Esposito |
| collection | DOAJ |
| description | We investigated the effect of lockdown measures implemented in Lombardy on selected obstetric and perinatal outcomes. Births that occurred during the two lockdowns imposed (i.e., the first from 16 March to 2 June 2020 and the second from 3 November 2020 to 5 April 2021) and the comparison periods (i.e., the first from 16 March to 2 June 2018 and the second from 3 November 2018 to 5 April 2019) were identified using regional healthcare databases. The distribution of births according to the selected outcomes was computed and the Chi-square test was used for testing differences in the periods compared. During the two lockdowns, we observed a lower proportion of low birth weight, from 6.8% in the comparison period to 6.1% in the first lockdown (<i>p</i> = 0.019), and from 6.5% to 6.1% in the second one (<i>p</i> = 0.109). The proportion of preterm births decreased from 6.8% to 6.3% in the first lockdown (<i>p</i> = 0.097), and from 6.2% to 6.0% in the second one (<i>p</i> = 0.172). No differences in stillbirth rate emerged for both lockdowns. Induction of labor was more frequent during both lockdowns, from 28.6% to 32.7% in the first (<i>p</i> < 0.0001), and from 29.9% to 33.2% in the second one (<i>p</i> < 0.0001). Cesarean section was less frequent during the second lockdown. |
| first_indexed | 2024-03-11T06:19:42Z |
| format | Article |
| id | doaj.art-f5d811a61af84c13b29d517543acee41 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-11T06:19:42Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-f5d811a61af84c13b29d517543acee412023-11-17T12:03:12ZengMDPI AGJournal of Personalized Medicine2075-44262023-03-0113349910.3390/jpm13030499Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, ItalyGiovanna Esposito0Marta Rossi1Alessandro Favilli2Matteo Franchi3Giovanni Corrao4Fabio Parazzini5Carlo La Vecchia6Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalySection of Obstetrics and Gynecology, Department of Medicine and Surgery, University of Perugia, 06156 Perugia, ItalyUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, 20126 Milan, ItalyUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, 20126 Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyWe investigated the effect of lockdown measures implemented in Lombardy on selected obstetric and perinatal outcomes. Births that occurred during the two lockdowns imposed (i.e., the first from 16 March to 2 June 2020 and the second from 3 November 2020 to 5 April 2021) and the comparison periods (i.e., the first from 16 March to 2 June 2018 and the second from 3 November 2018 to 5 April 2019) were identified using regional healthcare databases. The distribution of births according to the selected outcomes was computed and the Chi-square test was used for testing differences in the periods compared. During the two lockdowns, we observed a lower proportion of low birth weight, from 6.8% in the comparison period to 6.1% in the first lockdown (<i>p</i> = 0.019), and from 6.5% to 6.1% in the second one (<i>p</i> = 0.109). The proportion of preterm births decreased from 6.8% to 6.3% in the first lockdown (<i>p</i> = 0.097), and from 6.2% to 6.0% in the second one (<i>p</i> = 0.172). No differences in stillbirth rate emerged for both lockdowns. Induction of labor was more frequent during both lockdowns, from 28.6% to 32.7% in the first (<i>p</i> < 0.0001), and from 29.9% to 33.2% in the second one (<i>p</i> < 0.0001). Cesarean section was less frequent during the second lockdown.https://www.mdpi.com/2075-4426/13/3/499COVID-19lockdownperinatal outcomeslabordelivery |
| spellingShingle | Giovanna Esposito Marta Rossi Alessandro Favilli Matteo Franchi Giovanni Corrao Fabio Parazzini Carlo La Vecchia Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy Journal of Personalized Medicine COVID-19 lockdown perinatal outcomes labor delivery |
| title | Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy |
| title_full | Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy |
| title_fullStr | Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy |
| title_full_unstemmed | Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy |
| title_short | Impact of the First and Second Lockdown for COVID-19 Pandemic on Preterm Birth, Low Birth Weight, Stillbirth, Mode of Labor, and of Delivery in Lombardy, Italy |
| title_sort | impact of the first and second lockdown for covid 19 pandemic on preterm birth low birth weight stillbirth mode of labor and of delivery in lombardy italy |
| topic | COVID-19 lockdown perinatal outcomes labor delivery |
| url | https://www.mdpi.com/2075-4426/13/3/499 |
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