Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation

Glycoprotein-2 (GP-2) can protect the intestinal epithelial barrier from bacteria and is associated with protection against Crohn’s disease. Here, the authors show pancreatic GP-2 is the source of the intestine’s luminal GP-2 that binds bacteria and prevents them from attaching to the epithelium, al...

詳細記述

書誌詳細
主要な著者: Yosuke Kurashima, Takaaki Kigoshi, Sayuri Murasaki, Fujimi Arai, Kaoru Shimada, Natsumi Seki, Yun-Gi Kim, Koji Hase, Hiroshi Ohno, Kazuya Kawano, Hiroshi Ashida, Toshihiko Suzuki, Masako Morimoto, Yukari Saito, Ai Sasou, Yuki Goda, Yoshikazu Yuki, Yutaka Inagaki, Hideki Iijima, Wataru Suda, Masahira Hattori, Hiroshi Kiyono
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2021-02-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-021-21277-2