Axonal Spectrins: Nanoscale Organization, Functional Domains and Spectrinopathies

Axonal Spectrins: Nanoscale Organization, Functional Domains and Spectrinopathies

Spectrin cytoskeletons are found in all metazoan cells, and their physical interactions between actin and ankyrins establish a meshwork that provides cellular structural integrity. With advanced super-resolution microscopy, the intricate spatial organization and associated functional properties of t...

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Bibliographic Details
Main Authors: Cheng-Hsin Liu, Matthew Neil Rasband
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spectrin
super-resolution microscopy
axonal excitable domains
axon integrity
spectrinopathy
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00234/full

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