Diabetes impairs the protective effects of sevoflurane postconditioning in the myocardium subjected to ischemia/ reperfusion injury in rats: important role of Drp1

Abstract Background Sevoflurane postconditioning (SevP) effectively relieves myocardial ischemia/reperfusion (I/R) injury but performs poorly in the diabetic myocardium. Previous studies have revealed the important role of increased oxidative stress in diabetic tissues. Notably, mitochondrial fissio...

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Bibliographic Details
Main Authors: Jing Yu, Jiandong He, Wenqu Yang, Xiang Wang, Gaoxiang Shi, Yinglei Duan, Hui Wang, Chongfang Han
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-021-01906-w

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