Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst
A highly efficient, inexpensive, recyclable, convenient, and green protocol for chemoselective aza-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using silica sulfuric acid (SSA or SiO2-SO3H) was developed. This method is simple, convenient and the title compounds are produ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2009-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/14/11/4779/ |
| _version_ | 1818347459670179840 |
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| author | Sheng-Rong Guo Yan-Qin Yuan Yan Wang |
| author_facet | Sheng-Rong Guo Yan-Qin Yuan Yan Wang |
| author_sort | Sheng-Rong Guo |
| collection | DOAJ |
| description | A highly efficient, inexpensive, recyclable, convenient, and green protocol for chemoselective aza-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using silica sulfuric acid (SSA or SiO2-SO3H) was developed. This method is simple, convenient and the title compounds are produced in good to excellent yields. |
| first_indexed | 2024-12-13T17:34:30Z |
| format | Article |
| id | doaj.art-f5dfc68800694d239aecd1e37c7eb599 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T17:34:30Z |
| publishDate | 2009-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f5dfc68800694d239aecd1e37c7eb5992022-12-21T23:36:58ZengMDPI AGMolecules1420-30492009-11-0114114779478910.3390/molecules14114779Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable CatalystSheng-Rong GuoYan-Qin YuanYan WangA highly efficient, inexpensive, recyclable, convenient, and green protocol for chemoselective aza-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using silica sulfuric acid (SSA or SiO2-SO3H) was developed. This method is simple, convenient and the title compounds are produced in good to excellent yields.http://www.mdpi.com/1420-3049/14/11/4779/aminesthiolssilica sulfuric acid (SSA)Michael reactionα,β-unsaturated olefins |
| spellingShingle | Sheng-Rong Guo Yan-Qin Yuan Yan Wang Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst Molecules amines thiols silica sulfuric acid (SSA) Michael reaction α,β-unsaturated olefins |
| title | Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst |
| title_full | Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst |
| title_fullStr | Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst |
| title_full_unstemmed | Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst |
| title_short | Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst |
| title_sort | silica sulfuric acid promotes aza michael addition reactions under solvent free condition as a heterogeneous and reusable catalyst |
| topic | amines thiols silica sulfuric acid (SSA) Michael reaction α,β-unsaturated olefins |
| url | http://www.mdpi.com/1420-3049/14/11/4779/ |
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