Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet
Objectives : The brain damage associated with schizophrenia has been established beyond doubt; however, what remains unexplored is the biological nature of transcultural variations. An important reason for this was the lack of mid and high field scanners in developing countries like India. Material...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2006-08-01
|
| Series: | Indian Journal of Radiology and Imaging |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.29000 |
| _version_ | 1828916731266990080 |
|---|---|
| author | S R Parkar R Seethalakshmi H Shah |
| author_facet | S R Parkar R Seethalakshmi H Shah |
| author_sort | S R Parkar |
| collection | DOAJ |
| description | Objectives : The brain damage associated with schizophrenia has been established beyond doubt; however, what remains unexplored is the biological nature of transcultural variations. An important reason for this was the lack of mid and high field scanners in developing countries like India.
Material and Methods : We undertook a pilot study using a 0.5 Tesla MRI scanner (General Electric Signa Contour) to explore identifiable structural brain lesions in ten randomly selected individuals with schizophrenia.
Results: Nine of the ten participants in the series had structural brain changes. The most common findings were ventricular dilatation and prominent cerebral cortical sulci and cerebellar folia. Additionally non-focal white matter lesions were observed in three patients and small right hippocampus was noted in one participant.
Conclusions : The study discusses that establishing structural brain lesions with mid field scanners is indeed feasible. The small study sample and heterogeneity of schizophrenia however made it difficult to establish any definite associations |
| first_indexed | 2024-12-13T20:38:44Z |
| format | Article |
| id | doaj.art-f5e32aedff2c4526a0a461cf8865af70 |
| institution | Directory Open Access Journal |
| issn | 0971-3026 1998-3808 |
| language | English |
| last_indexed | 2024-12-13T20:38:44Z |
| publishDate | 2006-08-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Radiology and Imaging |
| spelling | doaj.art-f5e32aedff2c4526a0a461cf8865af702022-12-21T23:32:13ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Radiology and Imaging0971-30261998-38082006-08-01160329930110.4103/0971-3026.29000Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnetS R Parkar0R Seethalakshmi1H Shah2Department of Psychiatry, Seth GS Medical College and KEM Hospital, Parel, Mumbai, IndiaDepartment of Psychiatry, Seth GS Medical College and KEM Hospital, Parel, Mumbai, IndiaDepartment of Psychiatry, Seth GS Medical College and KEM Hospital, Parel, Mumbai, IndiaObjectives : The brain damage associated with schizophrenia has been established beyond doubt; however, what remains unexplored is the biological nature of transcultural variations. An important reason for this was the lack of mid and high field scanners in developing countries like India. Material and Methods : We undertook a pilot study using a 0.5 Tesla MRI scanner (General Electric Signa Contour) to explore identifiable structural brain lesions in ten randomly selected individuals with schizophrenia. Results: Nine of the ten participants in the series had structural brain changes. The most common findings were ventricular dilatation and prominent cerebral cortical sulci and cerebellar folia. Additionally non-focal white matter lesions were observed in three patients and small right hippocampus was noted in one participant. Conclusions : The study discusses that establishing structural brain lesions with mid field scanners is indeed feasible. The small study sample and heterogeneity of schizophrenia however made it difficult to establish any definite associationshttp://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.29000schizophreniamrimid field scanners |
| spellingShingle | S R Parkar R Seethalakshmi H Shah Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet Indian Journal of Radiology and Imaging schizophrenia mri mid field scanners |
| title | Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet |
| title_full | Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet |
| title_fullStr | Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet |
| title_full_unstemmed | Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet |
| title_short | Structural brain lesions in schizophrenia -magnetic resonance imaging on a mid field magnet |
| title_sort | structural brain lesions in schizophrenia magnetic resonance imaging on a mid field magnet |
| topic | schizophrenia mri mid field scanners |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.29000 |
| work_keys_str_mv | AT srparkar structuralbrainlesionsinschizophreniamagneticresonanceimagingonamidfieldmagnet AT rseethalakshmi structuralbrainlesionsinschizophreniamagneticresonanceimagingonamidfieldmagnet AT hshah structuralbrainlesionsinschizophreniamagneticresonanceimagingonamidfieldmagnet |