Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attack...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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Series: | Indian Journal of Dermatology |
Subjects: | |
Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chen |
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author | Dawei Chen Chun Wang Lina Cui Xingwu Ran |
author_facet | Dawei Chen Chun Wang Lina Cui Xingwu Ran |
author_sort | Dawei Chen |
collection | DOAJ |
description | Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing. |
first_indexed | 2024-12-11T14:13:35Z |
format | Article |
id | doaj.art-f5e33be0cbf9497298ab7ff5214cc1dc |
institution | Directory Open Access Journal |
issn | 0019-5154 1998-3611 |
language | English |
last_indexed | 2024-12-11T14:13:35Z |
publishDate | 2020-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Dermatology |
spelling | doaj.art-f5e33be0cbf9497298ab7ff5214cc1dc2022-12-22T01:03:18ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112020-01-0165214114410.4103/ijd.IJD_157_18Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous goutDawei ChenChun WangLina CuiXingwu RanUlcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chenautologous patelet-rich gelgoutplatelet–rich plasmatophus ulcer |
spellingShingle | Dawei Chen Chun Wang Lina Cui Xingwu Ran Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout Indian Journal of Dermatology autologous patelet-rich gel gout platelet–rich plasma tophus ulcer |
title | Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
title_full | Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
title_fullStr | Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
title_full_unstemmed | Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
title_short | Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
title_sort | autologous platelet rich gel treatment of chronic nonhealing ulcerated tophaceous gout |
topic | autologous patelet-rich gel gout platelet–rich plasma tophus ulcer |
url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chen |
work_keys_str_mv | AT daweichen autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout AT chunwang autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout AT linacui autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout AT xingwuran autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout |