Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout

Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attack...

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Main Authors: Dawei Chen, Chun Wang, Lina Cui, Xingwu Ran
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chen
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author Dawei Chen
Chun Wang
Lina Cui
Xingwu Ran
author_facet Dawei Chen
Chun Wang
Lina Cui
Xingwu Ran
author_sort Dawei Chen
collection DOAJ
description Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing.
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spelling doaj.art-f5e33be0cbf9497298ab7ff5214cc1dc2022-12-22T01:03:18ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112020-01-0165214114410.4103/ijd.IJD_157_18Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous goutDawei ChenChun WangLina CuiXingwu RanUlcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chenautologous patelet-rich gelgoutplatelet–rich plasmatophus ulcer
spellingShingle Dawei Chen
Chun Wang
Lina Cui
Xingwu Ran
Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
Indian Journal of Dermatology
autologous patelet-rich gel
gout
platelet–rich plasma
tophus ulcer
title Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
title_full Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
title_fullStr Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
title_full_unstemmed Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
title_short Autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
title_sort autologous platelet rich gel treatment of chronic nonhealing ulcerated tophaceous gout
topic autologous patelet-rich gel
gout
platelet–rich plasma
tophus ulcer
url http://www.e-ijd.org/article.asp?issn=0019-5154;year=2020;volume=65;issue=2;spage=141;epage=144;aulast=Chen
work_keys_str_mv AT daweichen autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout
AT chunwang autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout
AT linacui autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout
AT xingwuran autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout