The Mouse CircGHR Regulates Proliferation, Differentiation and Apoptosis of Hepatocytes and Myoblasts

The Mouse CircGHR Regulates Proliferation, Differentiation and Apoptosis of Hepatocytes and Myoblasts

The anterior pituitary gland of animals secretes growth hormone (GH) to bind to the growth hormone receptor (GHR) on the liver cell membrane through the blood circulation, thereby promoting the downstream gene insulin-like growth factor-1 (IGF1) expression, which is the canonical GH–GHR–IGF1 signali...

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Bibliographic Details
Main Authors: Weilu Zhang, Shudai Lin, Zhenhai Jiao, Lilong An, Tingting Xie, Jiang Wu, Li Zhang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Genes
Subjects:
mouse
circGHR
NCTC1469
C2C12
cell proliferation
Online Access:https://www.mdpi.com/2073-4425/14/6/1207

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