Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats
Background & objectives: Fenugreek (Trigonella foenum-graecum) is one of the most ancient and well-known medicinal plants, and its useful role has been well - established in treating of many diseases. The purpose of this study was to investigate the effect of Fenugreek on spermatogenesis, total...
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Ardabil University of Medical Sciences
2022-12-01
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| Series: | Journal of Ardabil University of Medical Sciences |
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| Online Access: | http://jarums.arums.ac.ir/article-1-2106-en.html |
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| author | Parisa Ghahremani Hemen Moradi Sardareh Hashem Yaghoubi Neda Farazi Asadullah Asady |
| author_facet | Parisa Ghahremani Hemen Moradi Sardareh Hashem Yaghoubi Neda Farazi Asadullah Asady |
| author_sort | Parisa Ghahremani |
| collection | DOAJ |
| description | Background & objectives: Fenugreek (Trigonella foenum-graecum) is one of the most ancient and well-known medicinal plants, and its useful role has been well - established in treating of many diseases. The purpose of this study was to investigate the effect of Fenugreek on spermatogenesis, total antioxidant capacity and malondialdehyde (MDA) level in male diabetic rats.
Methods: In this experimental study, 24 male Wistar rats weighing approximately 200±20 gram were used. The rats were randomly divided into 4 groups of six. group1: control group, Group2: diabetic, Group3: diabetic+Fenugreek (8gram /kg diet), group4: diabetic+Fenugreek (2gram /kg diet). This treatment continued for 4 weeks. Blood glucose, total antioxidant capacity, malondialdehyde, and sperm profiles were determined.
Results: Blood glucose in diabetic rats which received Fenugreek significantly reduced compared with diabetic animals. Fenugreek also reduced body weight and MDA level of semen (p<0.05).On the other hand, Fenugreek increased the total antioxidant capacity of semen (p<0.05) and normalized sperm profiles (p<0.05).
Conclusion: According to the present results, it can be concluded that consumption of Fenugreek extract probably reduced MDA level, body weight, and normalized sperm profile thus, Fenugreek extract can be used to treat sexual dysfunction in males. |
| first_indexed | 2024-04-09T12:54:23Z |
| format | Article |
| id | doaj.art-f5eeeda721b0476480b1c401348fbee1 |
| institution | Directory Open Access Journal |
| issn | 2228-7280 2228-7299 |
| language | fas |
| last_indexed | 2024-04-09T12:54:23Z |
| publishDate | 2022-12-01 |
| publisher | Ardabil University of Medical Sciences |
| record_format | Article |
| series | Journal of Ardabil University of Medical Sciences |
| spelling | doaj.art-f5eeeda721b0476480b1c401348fbee12023-05-14T04:48:14ZfasArdabil University of Medical SciencesJournal of Ardabil University of Medical Sciences2228-72802228-72992022-12-01224333348Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II RatsParisa Ghahremani0Hemen Moradi Sardareh1Hashem Yaghoubi2Neda Farazi3Asadullah Asady4 Department of Biology, Payame Noor University, East Tehran Branch, Iran Department of Basic Sciences, Asadabad School of Medical Sciences, Asadabad, Iran Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran Background & objectives: Fenugreek (Trigonella foenum-graecum) is one of the most ancient and well-known medicinal plants, and its useful role has been well - established in treating of many diseases. The purpose of this study was to investigate the effect of Fenugreek on spermatogenesis, total antioxidant capacity and malondialdehyde (MDA) level in male diabetic rats. Methods: In this experimental study, 24 male Wistar rats weighing approximately 200±20 gram were used. The rats were randomly divided into 4 groups of six. group1: control group, Group2: diabetic, Group3: diabetic+Fenugreek (8gram /kg diet), group4: diabetic+Fenugreek (2gram /kg diet). This treatment continued for 4 weeks. Blood glucose, total antioxidant capacity, malondialdehyde, and sperm profiles were determined. Results: Blood glucose in diabetic rats which received Fenugreek significantly reduced compared with diabetic animals. Fenugreek also reduced body weight and MDA level of semen (p<0.05).On the other hand, Fenugreek increased the total antioxidant capacity of semen (p<0.05) and normalized sperm profiles (p<0.05). Conclusion: According to the present results, it can be concluded that consumption of Fenugreek extract probably reduced MDA level, body weight, and normalized sperm profile thus, Fenugreek extract can be used to treat sexual dysfunction in males.http://jarums.arums.ac.ir/article-1-2106-en.htmlantioxidantspermtestisdiabetesrataqueous extract of fenugreek |
| spellingShingle | Parisa Ghahremani Hemen Moradi Sardareh Hashem Yaghoubi Neda Farazi Asadullah Asady Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats Journal of Ardabil University of Medical Sciences antioxidant sperm testis diabetes rat aqueous extract of fenugreek |
| title | Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats |
| title_full | Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats |
| title_fullStr | Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats |
| title_full_unstemmed | Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats |
| title_short | Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats |
| title_sort | investigating fenugreek seed aqueous extract on sperm parameters in selected type ii rats |
| topic | antioxidant sperm testis diabetes rat aqueous extract of fenugreek |
| url | http://jarums.arums.ac.ir/article-1-2106-en.html |
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