Diagnostics and Treatment of Cerebral Venous Thrombosis

BACKGROUND This article is devoted to the discussion of a life-threatening and difficult to diagnose disease — cerebral venous thrombosis (CVT). The article lists clinical manifestations, features of diagnosis and treatment of CVT. Cerebral venous thrombosis is an emergency that requires a quick dec...

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Main Authors: G. R. Ramazanov, Kh. V. Korigova, S. S. Petrikov
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2021-04-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/1080
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author G. R. Ramazanov
Kh. V. Korigova
S. S. Petrikov
author_facet G. R. Ramazanov
Kh. V. Korigova
S. S. Petrikov
author_sort G. R. Ramazanov
collection DOAJ
description BACKGROUND This article is devoted to the discussion of a life-threatening and difficult to diagnose disease — cerebral venous thrombosis (CVT). The article lists clinical manifestations, features of diagnosis and treatment of CVT. Cerebral venous thrombosis is an emergency that requires a quick decision to start therapy in order to prevent the development of venous cerebral infarction, intracranial hemorrhage, severe disability and death. Cerebral venous thrombosis is a rare and rather difficult to recognize form of acute cerebrovascular accident (ACVA). Considering the variability of the clinical and radiological picture, as well as the large number of risk factors, CVT is a complex medical problem. Despite the fact that CVTs account for less than 1% of all ACVA, significant differences in treatment necessitatethe earliest possible differential diagnosis of CVT with arterial stroke. The diagnosis is often made with a delay due to a wide range of clinical manifestations, subacute onset of the disease, as well as low alertness of specialists in relation to CVT. In patients with cryptogenic stroke, CVT should be ruled out as a potential cause of stroke. Among other things, in the case of CVT, as in the case of thrombosis of the cerebral arteries, the establishment of the leading etiological factor is one of the priority tasks, the solution of which allows choosing the optimal means of secondary prevention. AIM OF STUDY Raising awareness of doctors of multidisciplinary hospitals about clinical manifestations, methods of diagnosis and treatment of CVT.MATERIAl AND METHODS To achieve this goal, the results of domestic and foreign scientific research on the diagno-sis and treatment of CVT were analyzed. Literature searches were carried out in electronic search engines Scopus, eLibrary, PubMed using the keywords: cerebral venous thrombosis, cryptogenic stroke, intracerebral hemorrhage, anticoagulant therapy, neurological imaging in cerebral venous thrombosis. For the analysis, scientific articles published between 1828 and 2020 were selected. Thirty percent of the analyzed works on the subject of CVT are not older than 5 years.CONClUSION Due to the various clinical manifestations and the absence of pathognomonic symptoms, neuroimaging plays a leading role in establishing the diagnosis. Early diagnosis of cerebral venous thrombosis and the use of anticoagulants lead to a decrease in disability and mortality.
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spelling doaj.art-f5f3664cdcef4420b94976d95c65b80d2025-03-02T11:06:21ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172021-04-0110112213410.23934/2223-9022-2021-10-1-122-134662Diagnostics and Treatment of Cerebral Venous ThrombosisG. R. Ramazanov0Kh. V. Korigova1S. S. Petrikov2N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health DepartmentBACKGROUND This article is devoted to the discussion of a life-threatening and difficult to diagnose disease — cerebral venous thrombosis (CVT). The article lists clinical manifestations, features of diagnosis and treatment of CVT. Cerebral venous thrombosis is an emergency that requires a quick decision to start therapy in order to prevent the development of venous cerebral infarction, intracranial hemorrhage, severe disability and death. Cerebral venous thrombosis is a rare and rather difficult to recognize form of acute cerebrovascular accident (ACVA). Considering the variability of the clinical and radiological picture, as well as the large number of risk factors, CVT is a complex medical problem. Despite the fact that CVTs account for less than 1% of all ACVA, significant differences in treatment necessitatethe earliest possible differential diagnosis of CVT with arterial stroke. The diagnosis is often made with a delay due to a wide range of clinical manifestations, subacute onset of the disease, as well as low alertness of specialists in relation to CVT. In patients with cryptogenic stroke, CVT should be ruled out as a potential cause of stroke. Among other things, in the case of CVT, as in the case of thrombosis of the cerebral arteries, the establishment of the leading etiological factor is one of the priority tasks, the solution of which allows choosing the optimal means of secondary prevention. AIM OF STUDY Raising awareness of doctors of multidisciplinary hospitals about clinical manifestations, methods of diagnosis and treatment of CVT.MATERIAl AND METHODS To achieve this goal, the results of domestic and foreign scientific research on the diagno-sis and treatment of CVT were analyzed. Literature searches were carried out in electronic search engines Scopus, eLibrary, PubMed using the keywords: cerebral venous thrombosis, cryptogenic stroke, intracerebral hemorrhage, anticoagulant therapy, neurological imaging in cerebral venous thrombosis. For the analysis, scientific articles published between 1828 and 2020 were selected. Thirty percent of the analyzed works on the subject of CVT are not older than 5 years.CONClUSION Due to the various clinical manifestations and the absence of pathognomonic symptoms, neuroimaging plays a leading role in establishing the diagnosis. Early diagnosis of cerebral venous thrombosis and the use of anticoagulants lead to a decrease in disability and mortality.https://www.jnmp.ru/jour/article/view/1080cerebral venous thrombosiscryptogenic strokeintracerebral hemorrhageneuroimaging is not necessary for cerebral venous thrombosisanticoagulant therapy
spellingShingle G. R. Ramazanov
Kh. V. Korigova
S. S. Petrikov
Diagnostics and Treatment of Cerebral Venous Thrombosis
Неотложная медицинская помощь
cerebral venous thrombosis
cryptogenic stroke
intracerebral hemorrhage
neuroimaging is not necessary for cerebral venous thrombosis
anticoagulant therapy
title Diagnostics and Treatment of Cerebral Venous Thrombosis
title_full Diagnostics and Treatment of Cerebral Venous Thrombosis
title_fullStr Diagnostics and Treatment of Cerebral Venous Thrombosis
title_full_unstemmed Diagnostics and Treatment of Cerebral Venous Thrombosis
title_short Diagnostics and Treatment of Cerebral Venous Thrombosis
title_sort diagnostics and treatment of cerebral venous thrombosis
topic cerebral venous thrombosis
cryptogenic stroke
intracerebral hemorrhage
neuroimaging is not necessary for cerebral venous thrombosis
anticoagulant therapy
url https://www.jnmp.ru/jour/article/view/1080
work_keys_str_mv AT grramazanov diagnosticsandtreatmentofcerebralvenousthrombosis
AT khvkorigova diagnosticsandtreatmentofcerebralvenousthrombosis
AT sspetrikov diagnosticsandtreatmentofcerebralvenousthrombosis