Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications
The porosity and degradation rate are critical properties of biodegradable bone implants, as they facilitate the regeneration of bone tissues and ensure a gradual load transfer. Herein, porous iron-hydroxyapatite (Fe-HA) metal-matrix composites (MMCs) with independently adjustable porosity and degra...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127522009418 |
| _version_ | 1811292148059865088 |
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| author | Chao Xu Mingyang Ban Hongye Zhang Qingping Liu Luquan Ren |
| author_facet | Chao Xu Mingyang Ban Hongye Zhang Qingping Liu Luquan Ren |
| author_sort | Chao Xu |
| collection | DOAJ |
| description | The porosity and degradation rate are critical properties of biodegradable bone implants, as they facilitate the regeneration of bone tissues and ensure a gradual load transfer. Herein, porous iron-hydroxyapatite (Fe-HA) metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate are fabricated through a 3D printing technique, i.e., direct ink writing (DIW). HA micro powders exhibit a significant acceleration effect on the degradation rate, which act as a variable that is independent of the porosity to regulate the degradation rate. The mass losses of Fe-HA MMCs with the porosities of 30%, 50%, and 70% after 21d in-vitro immersion increased by 26%, 38%, and 93%, respectively, with the rising of HA content from 0 to 7.5 wt%. The novel porous Fe-HA MMCs have an adjustable and wide porosity-degradation rate range, yielding great potential to match with varied porosity and regeneration rate among various bones of different people. |
| first_indexed | 2024-04-13T04:41:02Z |
| format | Article |
| id | doaj.art-f5f4c59a8dd34c908491abe8cc1304cc |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-04-13T04:41:02Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-f5f4c59a8dd34c908491abe8cc1304cc2022-12-22T03:01:59ZengElsevierMaterials & Design0264-12752022-12-01224111319Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applicationsChao Xu0Mingyang Ban1Hongye Zhang2Qingping Liu3Luquan Ren4Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, 130000, China; School of Mechanical and Aerospace Engineering, Jilin University, Changchun, 130000, China; Corresponding authors at: Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, China (C. Xu).School of Mechanical and Aerospace Engineering, Jilin University, Changchun, 130000, ChinaSchool of Mechanical and Aerospace Engineering, Jilin University, Changchun, 130000, ChinaKey Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, 130000, China; Corresponding authors at: Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, China (C. Xu).Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun, 130000, ChinaThe porosity and degradation rate are critical properties of biodegradable bone implants, as they facilitate the regeneration of bone tissues and ensure a gradual load transfer. Herein, porous iron-hydroxyapatite (Fe-HA) metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate are fabricated through a 3D printing technique, i.e., direct ink writing (DIW). HA micro powders exhibit a significant acceleration effect on the degradation rate, which act as a variable that is independent of the porosity to regulate the degradation rate. The mass losses of Fe-HA MMCs with the porosities of 30%, 50%, and 70% after 21d in-vitro immersion increased by 26%, 38%, and 93%, respectively, with the rising of HA content from 0 to 7.5 wt%. The novel porous Fe-HA MMCs have an adjustable and wide porosity-degradation rate range, yielding great potential to match with varied porosity and regeneration rate among various bones of different people.http://www.sciencedirect.com/science/article/pii/S0264127522009418Direct ink writing (DIW)Metal-matrix composites (MMCs)Porous Fe-HA scaffoldsDegradation ratePorosity |
| spellingShingle | Chao Xu Mingyang Ban Hongye Zhang Qingping Liu Luquan Ren Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications Materials & Design Direct ink writing (DIW) Metal-matrix composites (MMCs) Porous Fe-HA scaffolds Degradation rate Porosity |
| title | Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications |
| title_full | Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications |
| title_fullStr | Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications |
| title_full_unstemmed | Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications |
| title_short | Direct ink writing of porous Fe-HA metal-matrix composites (MMCs) with independently adjustable porosity and degradation rate for bone implant applications |
| title_sort | direct ink writing of porous fe ha metal matrix composites mmcs with independently adjustable porosity and degradation rate for bone implant applications |
| topic | Direct ink writing (DIW) Metal-matrix composites (MMCs) Porous Fe-HA scaffolds Degradation rate Porosity |
| url | http://www.sciencedirect.com/science/article/pii/S0264127522009418 |
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