Mecp2-null mice provide new neuronal targets for Rett syndrome.
BACKGROUND: Rett syndrome (RTT) is a complex neurological disorder that is one of the most frequent causes of mental retardation in women. A great landmark in research in this field was the discovery of a relationship between the disease and the presence of mutations in the gene that codes for the m...
Main Authors: | Rocio G Urdinguio, Lidia Lopez-Serra, Pilar Lopez-Nieva, Miguel Alaminos, Ramon Diaz-Uriarte, Agustin F Fernandez, Manel Esteller |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2576441?pdf=render |
Similar Items
-
QTc interval and ventricular action potential prolongation in the Mecp2Null/+ murine model of Rett syndrome
by: Hongwei Cheng, et al.
Published: (2022-10-01) -
Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2
by: David Ortega-Alarcon, et al.
Published: (2020-11-01) -
Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice
by: Noriyuki Kishi, et al.
Published: (2016-01-01) -
Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome
by: Chao-Yin Chen, et al.
Published: (2018-01-01) -
MECP2 Mutations and Rett Syndrome Phenotypes
by: J Gordon Millichap
Published: (2000-05-01)