Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents
Aim The aim of this study was to evaluate the safety and efficacy of low-dose (0.01%) topical atropine eye drops for slowing down the progression of myopia in children and adolescents. Patients and methods A total of 600 eyes of 300 patients aged from 8 to 14 years were included in the study. They w...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Delta Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.djo.eg.net/article.asp?issn=1110-9173;year=2021;volume=22;issue=1;spage=63;epage=67;aulast=Alhagaa |
| _version_ | 1818588521143730176 |
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| author | Ahmed A Alhagaa Nermeen M Badawi |
| author_facet | Ahmed A Alhagaa Nermeen M Badawi |
| author_sort | Ahmed A Alhagaa |
| collection | DOAJ |
| description | Aim The aim of this study was to evaluate the safety and efficacy of low-dose (0.01%) topical atropine eye drops for slowing down the progression of myopia in children and adolescents.
Patients and methods A total of 600 eyes of 300 patients aged from 8 to 14 years were included in the study. They were divided into two groups: group A, which included 300 myopic eyes with a spherical equivalent (SE) between −3.00 and −6.00 D that received low-dose (0.01%) topical atropine eye drops once daily for 1 year, and group B as a control group, which consisted of 300 myopic eyes (with SE between −3.00 and −6.00 D) that did not receive the topical atropine eye drops. Posttherapy follow-up for myopia progression was done at 6 months, 1, 1.5, 2, 2.5, and 3 years.
Results By the end of 3 years, the mean SE was −5.1±1.75 D in group A in comparison with −6.15±3.15 D in group B. The progression of myopia was significantly more in group B than in group A after 1 year of follow-up and continued with statistically significant difference till the end of the follow-up period. No significant changes in topography or pachymetry were reported in the present study. In addition, no complications related to the low-dose topical atropine drops (0.01%) were reported.
Conclusion The use of low-dose (0.01%) topical atropine eye drops was safe and effective in decreasing the progression of myopia in children and adolescents. |
| first_indexed | 2024-12-16T09:26:04Z |
| format | Article |
| id | doaj.art-f5f779d2eb3a4035940838c636797128 |
| institution | Directory Open Access Journal |
| issn | 1110-9173 2090-4835 |
| language | English |
| last_indexed | 2024-12-16T09:26:04Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delta Journal of Ophthalmology |
| spelling | doaj.art-f5f779d2eb3a4035940838c6367971282022-12-21T22:36:39ZengWolters Kluwer Medknow PublicationsDelta Journal of Ophthalmology1110-91732090-48352021-01-01221636710.4103/DJO.DJO_5_20Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescentsAhmed A AlhagaaNermeen M BadawiAim The aim of this study was to evaluate the safety and efficacy of low-dose (0.01%) topical atropine eye drops for slowing down the progression of myopia in children and adolescents. Patients and methods A total of 600 eyes of 300 patients aged from 8 to 14 years were included in the study. They were divided into two groups: group A, which included 300 myopic eyes with a spherical equivalent (SE) between −3.00 and −6.00 D that received low-dose (0.01%) topical atropine eye drops once daily for 1 year, and group B as a control group, which consisted of 300 myopic eyes (with SE between −3.00 and −6.00 D) that did not receive the topical atropine eye drops. Posttherapy follow-up for myopia progression was done at 6 months, 1, 1.5, 2, 2.5, and 3 years. Results By the end of 3 years, the mean SE was −5.1±1.75 D in group A in comparison with −6.15±3.15 D in group B. The progression of myopia was significantly more in group B than in group A after 1 year of follow-up and continued with statistically significant difference till the end of the follow-up period. No significant changes in topography or pachymetry were reported in the present study. In addition, no complications related to the low-dose topical atropine drops (0.01%) were reported. Conclusion The use of low-dose (0.01%) topical atropine eye drops was safe and effective in decreasing the progression of myopia in children and adolescents.http://www.djo.eg.net/article.asp?issn=1110-9173;year=2021;volume=22;issue=1;spage=63;epage=67;aulast=Alhagaaatropinedropsmyopiaprogression |
| spellingShingle | Ahmed A Alhagaa Nermeen M Badawi Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents Delta Journal of Ophthalmology atropine drops myopia progression |
| title | Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents |
| title_full | Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents |
| title_fullStr | Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents |
| title_full_unstemmed | Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents |
| title_short | Safety and efficacy of low-dose topical atropine for slowing down progression of myopia in children and adolescents |
| title_sort | safety and efficacy of low dose topical atropine for slowing down progression of myopia in children and adolescents |
| topic | atropine drops myopia progression |
| url | http://www.djo.eg.net/article.asp?issn=1110-9173;year=2021;volume=22;issue=1;spage=63;epage=67;aulast=Alhagaa |
| work_keys_str_mv | AT ahmedaalhagaa safetyandefficacyoflowdosetopicalatropineforslowingdownprogressionofmyopiainchildrenandadolescents AT nermeenmbadawi safetyandefficacyoflowdosetopicalatropineforslowingdownprogressionofmyopiainchildrenandadolescents |