Laser photoacoustic spectroscopy applications in breathomics

The breathomics approach to express-diagnosis of bronchopulmonary diseases based on spectral analysis of volatile organic compounds in a patient’s exhaled air is discussed. The basic demands and possible technical solutions to laser photoacoustic spectroscopy equipment in a framework of breathomics...

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Main Authors: Yury V. Kistenev, Alexey V. Borisov, Victor V. Nikolaev, Denis A. Vrazhnov, Dmytry A. Kuzmin
Format: Article
Language:English
Published: Samara National Research University 2019-03-01
Series:Journal of Biomedical Photonics & Engineering
Subjects:
Online Access:http://jbpe.ssau.ru/index.php/JBPE/article/view/3307
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author Yury V. Kistenev
Alexey V. Borisov
Victor V. Nikolaev
Denis A. Vrazhnov
Dmytry A. Kuzmin
author_facet Yury V. Kistenev
Alexey V. Borisov
Victor V. Nikolaev
Denis A. Vrazhnov
Dmytry A. Kuzmin
author_sort Yury V. Kistenev
collection DOAJ
description The breathomics approach to express-diagnosis of bronchopulmonary diseases based on spectral analysis of volatile organic compounds in a patient’s exhaled air is discussed. The basic demands and possible technical solutions to laser photoacoustic spectroscopy equipment in a framework of breathomics are presented. An example of differential diagnostics of the set of bronchopulmonary diseases, including lung cancer (LC) patients (N = 9); patients with chronic obstructive pulmonary disease (COPD) (N = 12); patients with pneumonia (N = 11) and a control group of healthy volunteers using breath air analysis by laser photoacoustic spectroscopy and machine learning is presented.
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spelling doaj.art-f5f7bf0a2f2e4f61ad428a46631a0dfc2022-12-22T01:55:08ZengSamara National Research UniversityJournal of Biomedical Photonics & Engineering2411-28442019-03-015110.18287/JBPE19.05.0103032984Laser photoacoustic spectroscopy applications in breathomicsYury V. Kistenev0Alexey V. Borisov1Victor V. Nikolaev2Denis A. Vrazhnov3Dmytry A. Kuzmin4Tomsk State University, Russia; Siberian State Medical University, Tomsk, RussiaTomsk State University, Russia; Siberian State Medical University, Tomsk, RussiaTomsk State University, Russia; Institute of Strength Physics and Materials Science of Siberian Branch of the RAS, Tomsk, RussiaTomsk State University, Russia; Institute of Strength Physics and Materials Science of Siberian Branch of the RAS, Tomsk, RussiaSiberian State Medical University, Tomsk, RussiaThe breathomics approach to express-diagnosis of bronchopulmonary diseases based on spectral analysis of volatile organic compounds in a patient’s exhaled air is discussed. The basic demands and possible technical solutions to laser photoacoustic spectroscopy equipment in a framework of breathomics are presented. An example of differential diagnostics of the set of bronchopulmonary diseases, including lung cancer (LC) patients (N = 9); patients with chronic obstructive pulmonary disease (COPD) (N = 12); patients with pneumonia (N = 11) and a control group of healthy volunteers using breath air analysis by laser photoacoustic spectroscopy and machine learning is presented.http://jbpe.ssau.ru/index.php/JBPE/article/view/3307Breathomicsexhaled air analysislaser photoacoustic spectroscopyoptical parametric oscillatormachine learninglung cancer
spellingShingle Yury V. Kistenev
Alexey V. Borisov
Victor V. Nikolaev
Denis A. Vrazhnov
Dmytry A. Kuzmin
Laser photoacoustic spectroscopy applications in breathomics
Journal of Biomedical Photonics & Engineering
Breathomics
exhaled air analysis
laser photoacoustic spectroscopy
optical parametric oscillator
machine learning
lung cancer
title Laser photoacoustic spectroscopy applications in breathomics
title_full Laser photoacoustic spectroscopy applications in breathomics
title_fullStr Laser photoacoustic spectroscopy applications in breathomics
title_full_unstemmed Laser photoacoustic spectroscopy applications in breathomics
title_short Laser photoacoustic spectroscopy applications in breathomics
title_sort laser photoacoustic spectroscopy applications in breathomics
topic Breathomics
exhaled air analysis
laser photoacoustic spectroscopy
optical parametric oscillator
machine learning
lung cancer
url http://jbpe.ssau.ru/index.php/JBPE/article/view/3307
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AT denisavrazhnov laserphotoacousticspectroscopyapplicationsinbreathomics
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