Viscous Cervical Environment-on-a-Chip for Selecting High-Quality Sperm from Human Semen

Viscous Cervical Environment-on-a-Chip for Selecting High-Quality Sperm from Human Semen

When ejaculated sperm travels through the vagina to the uterus, mucus secreted by the cervical canal generally filters out sperm having low motility and poor morphology. To investigate this selection principle in vivo, we developed a microfluidic sperm-sorting chip with a viscous medium (polyvinylpy...

Full description

Bibliographic Details
Main Authors: Manhee Lee, Jin Woo Park, Dongwon Kim, Hyojeong Kwon, Min Jeong Cho, Eun Ji Lee, Tai Eun Shin, Dae Keun Kim, Seungki Lee, Do Gyeung Byeun, Jung Jae Ko, Jae Ho Lee, Jung Kyu Choi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomedicines
Subjects:
human sperm
polyvinylpyrrolidone (PVP)
cervical mucus
sperm-sorting chip
motility
sperm-head vacuole
Online Access:https://www.mdpi.com/2227-9059/9/10/1439

Internet

https://www.mdpi.com/2227-9059/9/10/1439

Similar Items