Adenovirus-Vectored Capsid Proteins of the Serotype A Foot-and-Mouth Disease Virus Protect Guinea Pigs Against Challenge

Adenovirus-Vectored Capsid Proteins of the Serotype A Foot-and-Mouth Disease Virus Protect Guinea Pigs Against Challenge

Type A foot-and-mouth disease virus (FMDV) has been detected on China’s pig farms since 2015, and all suspected samples have been strain A/GDMM/CHA/2013. To overcome the shortcomings of inactive FMDV vaccines, we expressed the capsid protein precursor P1-2A and mutated viral 3C protease of FMDV stra...

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Bibliographic Details
Main Authors:	Yinli Xie, Huiyun Chang, Zhiyong Li, Yanming Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Microbiology
Subjects:	foot-and-mouth disease virus capsid proteins recombinant adenovirus mutated viral 3C protease cytokines IgA antibody
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01449/full

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