Multiple myeloma presenting as bilateral orbital proptosis

A 58-year-old-man presented with painful rapidly progressive bilateral proptosis with restricted ocular movements of 15 days duration. There was history of significant weight loss in the recent past. Computed tomography scan of the head and orbit revealed bilateral multiple, well-defined, round, sof...

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Main Authors: Malik Archana, Narang Subina, Handa Uma, Sood Sunandan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2009;volume=57;issue=5;spage=393;epage=395;aulast=Malik
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author Malik Archana
Narang Subina
Handa Uma
Sood Sunandan
author_facet Malik Archana
Narang Subina
Handa Uma
Sood Sunandan
author_sort Malik Archana
collection DOAJ
description A 58-year-old-man presented with painful rapidly progressive bilateral proptosis with restricted ocular movements of 15 days duration. There was history of significant weight loss in the recent past. Computed tomography scan of the head and orbit revealed bilateral multiple, well-defined, round, soft tissue masses, isointense with muscles in intraconal and extraconal space. Fine needle aspiration cytology and incision biopsy from the lesion, urine for Bence-Jones proteins and immunofixation clinched the diagnosis of multiple myeloma. Skeletal survey did not reveal any bony involvement. The diagnosis of multiple myeloma should be kept in mind in cases of bilateral proptosis. Bony involvement is not universal in cases of orbital myeloma. Early diagnosis can be established with extensive biochemical and histopathological investigations and timely treatment is life saving for these patients.
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spelling doaj.art-f5fd6db9c07f45ccb21b48807c469fb82022-12-22T03:54:13ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892009-01-01575393395Multiple myeloma presenting as bilateral orbital proptosisMalik ArchanaNarang SubinaHanda UmaSood SunandanA 58-year-old-man presented with painful rapidly progressive bilateral proptosis with restricted ocular movements of 15 days duration. There was history of significant weight loss in the recent past. Computed tomography scan of the head and orbit revealed bilateral multiple, well-defined, round, soft tissue masses, isointense with muscles in intraconal and extraconal space. Fine needle aspiration cytology and incision biopsy from the lesion, urine for Bence-Jones proteins and immunofixation clinched the diagnosis of multiple myeloma. Skeletal survey did not reveal any bony involvement. The diagnosis of multiple myeloma should be kept in mind in cases of bilateral proptosis. Bony involvement is not universal in cases of orbital myeloma. Early diagnosis can be established with extensive biochemical and histopathological investigations and timely treatment is life saving for these patients.http://www.ijo.in/article.asp?issn=0301-4738;year=2009;volume=57;issue=5;spage=393;epage=395;aulast=MalikBilateral proptosismultiple myelomaplasma cell dyscrasias.
spellingShingle Malik Archana
Narang Subina
Handa Uma
Sood Sunandan
Multiple myeloma presenting as bilateral orbital proptosis
Indian Journal of Ophthalmology
Bilateral proptosis
multiple myeloma
plasma cell dyscrasias.
title Multiple myeloma presenting as bilateral orbital proptosis
title_full Multiple myeloma presenting as bilateral orbital proptosis
title_fullStr Multiple myeloma presenting as bilateral orbital proptosis
title_full_unstemmed Multiple myeloma presenting as bilateral orbital proptosis
title_short Multiple myeloma presenting as bilateral orbital proptosis
title_sort multiple myeloma presenting as bilateral orbital proptosis
topic Bilateral proptosis
multiple myeloma
plasma cell dyscrasias.
url http://www.ijo.in/article.asp?issn=0301-4738;year=2009;volume=57;issue=5;spage=393;epage=395;aulast=Malik
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AT narangsubina multiplemyelomapresentingasbilateralorbitalproptosis
AT handauma multiplemyelomapresentingasbilateralorbitalproptosis
AT soodsunandan multiplemyelomapresentingasbilateralorbitalproptosis