Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome

Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome

Alport syndrome (AS) is a progressive inherited kidney disease characterized by hearing loss and ocular abnormalities. There are three forms of AS depending on inheritance mode: X-linked Alport syndrome (XLAS), autosomal recessive AS (ARAS), and autosomal dominant AS (ADAS). XLAS is caused by pathog...

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Bibliographic Details
Main Authors: Kandai Nozu, Yutaka Takaoka, Hirofumi Kai, Minoru Takasato, Kensuke Yabuuchi, Tomohiko Yamamura, Tomoko Horinouchi, Nana Sakakibara, Takeshi Ninchoji, China Nagano, Kazumoto Iijima
Format: Article
Language:English
Published: The Korean Society of Nephrology 2020-12-01
Series:Kidney Research and Clinical Practice
Subjects:
alport syndrome
glomerular basement membrane
induced pluripotent stem
splicing
Online Access:https://doi.org/10.23876/j.krcp.20.111

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