The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology
Background: Many research studies have investigated the antimicrobial activity of nanoparticles and herbal extracts on pathogenic bacteria. The aim of this study was to evaluate the antibacterial activity of silver nanoparticles in combination with L. angusifolia leaf extract against Escherichia col...
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| Format: | Article |
| Language: | English |
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Kerman University of Medical Sciences
2022-01-01
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| Series: | Journal of Kerman University of Medical Sciences |
| Subjects: | |
| Online Access: | https://jkmu.kmu.ac.ir/article_91858_fe942f8c46350c96e6f8060dd7d15eaa.pdf |
| _version_ | 1797790795408867328 |
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| author | Foozieh Moghadami Mahdi Kalantari |
| author_facet | Foozieh Moghadami Mahdi Kalantari |
| author_sort | Foozieh Moghadami |
| collection | DOAJ |
| description | Background: Many research studies have investigated the antimicrobial activity of nanoparticles and herbal extracts on pathogenic bacteria. The aim of this study was to evaluate the antibacterial activity of silver nanoparticles in combination with L. angusifolia leaf extract against Escherichia coli and Staphylococcus aureus using response surface methodology.Methods: To evaluate the antibacterial activity of silver nanoparticles and L. angusifolia extract at different pH values against E.coli and S. aureus, the response surface methodology was used along with a central composite design. Agar well diffusion method was used to determine the antibacterial activity. Results: The results showed that the antibacterial activity of the combination of silver nanoparticles and L. angusifolia extract on E.coli (15.4 - 23.6 mm) was greater than that on S. aureus (11.7 – 21.6 mm). In addition, the antibacterial activity of the silver nanoparticles against E. coli and S. aureus was higher than that of L. angusifolia extract. The pH values had no effect on the antibacterial activity of the silver nanoparticles and L. angusifolia extract.Conclusion: The findings of this study showed that the combination of silver nanoparticles and L. angusifolia extract could be used as a possible source of effective antibacterial agent in infections. |
| first_indexed | 2024-03-13T02:09:37Z |
| format | Article |
| id | doaj.art-f60203ddd2834031970fbde7782232fa |
| institution | Directory Open Access Journal |
| issn | 2008-2843 |
| language | English |
| last_indexed | 2024-03-13T02:09:37Z |
| publishDate | 2022-01-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Journal of Kerman University of Medical Sciences |
| spelling | doaj.art-f60203ddd2834031970fbde7782232fa2023-07-01T05:10:53ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432022-01-012911910.22062/jkmu.2022.9185891858The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface MethodologyFoozieh Moghadami0Mahdi Kalantari1Department of Biology, Payame Noor University, Tehran, IranDepartment of Statistics, Payame Noor University, Tehran, IranBackground: Many research studies have investigated the antimicrobial activity of nanoparticles and herbal extracts on pathogenic bacteria. The aim of this study was to evaluate the antibacterial activity of silver nanoparticles in combination with L. angusifolia leaf extract against Escherichia coli and Staphylococcus aureus using response surface methodology.Methods: To evaluate the antibacterial activity of silver nanoparticles and L. angusifolia extract at different pH values against E.coli and S. aureus, the response surface methodology was used along with a central composite design. Agar well diffusion method was used to determine the antibacterial activity. Results: The results showed that the antibacterial activity of the combination of silver nanoparticles and L. angusifolia extract on E.coli (15.4 - 23.6 mm) was greater than that on S. aureus (11.7 – 21.6 mm). In addition, the antibacterial activity of the silver nanoparticles against E. coli and S. aureus was higher than that of L. angusifolia extract. The pH values had no effect on the antibacterial activity of the silver nanoparticles and L. angusifolia extract.Conclusion: The findings of this study showed that the combination of silver nanoparticles and L. angusifolia extract could be used as a possible source of effective antibacterial agent in infections.https://jkmu.kmu.ac.ir/article_91858_fe942f8c46350c96e6f8060dd7d15eaa.pdfsilver nanoparticlel.angusifoliaantibacterialresponse surface methodology |
| spellingShingle | Foozieh Moghadami Mahdi Kalantari The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology Journal of Kerman University of Medical Sciences silver nanoparticle l.angusifolia antibacterial response surface methodology |
| title | The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology |
| title_full | The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology |
| title_fullStr | The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology |
| title_full_unstemmed | The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology |
| title_short | The Evaluation of Antibacterial Activity of Silver Nanoparticle in Combination with Lavandula angusifolia Extract through Response Surface Methodology |
| title_sort | evaluation of antibacterial activity of silver nanoparticle in combination with lavandula angusifolia extract through response surface methodology |
| topic | silver nanoparticle l.angusifolia antibacterial response surface methodology |
| url | https://jkmu.kmu.ac.ir/article_91858_fe942f8c46350c96e6f8060dd7d15eaa.pdf |
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