| Summary: | The finding of diabetes in association with a pancreatic neuroendocrine tumor (PNET) in patients is uncommon. Here, we describe a 74-year-old diabetes patient with a tumor in the pancreatic head. Calcification in the central part of the tumor and significant expansion of the pancreatic duct were also detected. In addition, the patient had a gallstone, which was surgically resected. During surgery, the pancreatic tumor was biopsied. DNA was extracted from peripheral leukocytes, and MEN1 was excluded by direct sequencing of the MEN1 gene. After biochemical and immunohistochemical analyses, a pancreatic somatostatin tumor was diagnosed. Keywords: Specific type, Diabetes, Pancreatic somatostatin tumor
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