SNAI2 Attenuated the Stem-like Phenotype by Reducing the Expansion of EPCAM<sup>high</sup> Cells in Cervical Cancer Cells

SNAI2 Attenuated the Stem-like Phenotype by Reducing the Expansion of EPCAM<sup>high</sup> Cells in Cervical Cancer Cells

SNAI2 (Snai2) is a zinc-finger transcriptional repressor that belongs to the Snail family. The accumulated evidence suggests that SNAI2 exhibits biphasic effects on regulating a stem-like phenotype in various types of cells, both normal and malignant. In this study, by exogenously expressing SNAI2 i...

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Bibliographic Details
Main Authors: Xian Liu, Ni Zhang, Qian Chen, Qian Feng, Yanru Zhang, Zhiqiang Wang, Xiong Yue, Hongbao Li, Nan Cui
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
SNAI2
EPCAM
stem-like phenotype
β-catenin
cervical cancer
Online Access:https://www.mdpi.com/1422-0067/24/2/1062

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