Exenatide for obesity in children and adolescents: Systematic review and meta-analysis

Exenatide for obesity in children and adolescents: Systematic review and meta-analysis

Objectives: There is no curative treatment for childhood obesity. We aim to synthesize published Randomized Controlled Trials (RCTs) evidence on the efficacy of exenatide in obese children and adolescents.Methods: We conducted a comprehensive search and analysis of relevant studies in popular databa...

Full description

Bibliographic Details
Main Authors:	Bin Chen, Zhuan Zou, Xiaoyan Zhang, Dongqiong Xiao, Xihong Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Pharmacology
Subjects:	exenatide obesity efficacy child meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1290184/full

Similar Items

Efficacy and safety of blinatumomab in children with relapsed/refractory B cell acute lymphoblastic leukemia: A systematic review and meta-analysis
by: Bin Chen, et al.
Published: (2023-01-01)

Predictive value of neutrophil gelatinase-associated lipocalin in children with acute kidney injury: A systematic review and meta-analysis
by: Zhuan Zou, et al.
Published: (2023-03-01)

Accuracy of Machine Learning in Detecting Pediatric Epileptic Seizures: Systematic Review and Meta-Analysis
by: Zhuan Zou, et al.
Published: (2024-12-01)

New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it
by: Xingchun Wang, et al.
Published: (2017-04-01)

The Role of Vti1a in Biological Functions and Its Possible Role in Nervous System Disorders
by: Fajuan Tang, et al.
Published: (2022-05-01)

Effects of Exenatide vs. Metformin on endothelial function in obese patients with pre-diabetes: a randomized trial
by: Kelly Aaron S, et al.
Published: (2012-06-01)

The first successful desensitization protocol in exenatide allergy: a case report
by: Osman Ozan Yeğit, et al.
Published: (2023-01-01)

Weight Loss Outcomes Among Early High Responders to Exenatide Treatment: A Randomized, Placebo Controlled Study in Overweight and Obese Women
by: Megan Rodgers, et al.
Published: (2021-11-01)

Triple therapy for obese patients with type 2 diabetes: evaluating effectiveness of the metformin + exenatide + glibenclamide combination
by: M. B. Antsiferov, et al.
Published: (2015-12-01)

Exenatide Use in the Management of Type 2 Diabetes Mellitus
by: Angelos Kyriacou, et al.
Published: (2010-08-01)

Safety, Tolerability, and Proof-Of-Concept Study of OKV-119, a Novel Exenatide Long-Term Drug Delivery System, in Healthy Cats
by: Michael Klotsman, et al.
Published: (2021-05-01)

Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control
by: Rasmus Stenlid, et al.
Published: (2023-11-01)

Exenatide improves hepatocyte insulin resistance induced by different regional adipose tissue
by: Chuanmin Bai, et al.
Published: (2022-09-01)

New indications for exenatide therapy of type 2 diabetes mellitus
by: Olga Konstantinovna Vikulova, et al.
Published: (2010-09-01)

EFFECT OF PHARMACOLOGICAL PRECONDITIONING WITH INCRETINOMIMETICS EXENATIDE AND VILDAGLIPTIN ON THE SURVIVAL OF ISCHEMIC TISSUES
by: Alla Tarasova, et al.
Published: (2017-12-01)

Drug release profile of a novel exenatide long-term drug delivery system (OKV-119) administered to cats
by: Michael Klotsman, et al.
Published: (2024-05-01)

Association between exenatide use and incidence of Alzheimer's disease
by: Bo Zhou, et al.
Published: (2021-01-01)

Real-world glycemic outcomes in patients with type 2 diabetes initiating exenatide once weekly and liraglutide once daily: a retrospective cohort study
by: Saunders WB, et al.
Published: (2016-07-01)

Exenatide Microspheres for Monthly Controlled-Release Aided by Magnesium Hydroxide
by: Yuxuan Ge, et al.
Published: (2021-05-01)

Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice
by: Xiaoyan Bao, et al.
Published: (2020-04-01)

Effect of race on cardiometabolic responses to once-weekly exenatide: insights from the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)
by: Timothy M. E. Davis, et al.
Published: (2022-06-01)

Emerging role of GLP-1 receptor agonists in the treatment of obesity
by: Neff LM
Published: (2010-07-01)

Pharmalogical effects and results of clinical trials of the first incretinomimetic exenatide
by: Alexander Sergeevich Ametov, et al.
Published: (2011-09-01)

Target-mediated pharmacokinetic/pharmacodynamic model based meta-analysis and dosing regimen optimization of a long-acting release formulation of exenatide in patients with type 2 diabetes mellitus
by: Hanqing Li, et al.
Published: (2015-02-01)

Exenatide Attenuates Non-Alcoholic Steatohepatitis by Inhibiting the Pyroptosis Signaling Pathway
by: Yu Liu, et al.
Published: (2021-04-01)

Metagenomics study on taxonomic and functional change of gut microbiota in patients with obesity with PCOS treated with exenatide combination with metformin or metformin alone
by: Jingwen Gan, et al.
Published: (2023-12-01)

Effects of exenatide versus insulin glargine on body composition in overweight and obese T2DM patients: a randomized controlled trial
by: Ting-Ting Yin, et al.
Published: (2018-10-01)

An experimental study of exenatide effects on renal injury in diabetic rats
by: Xiaodong Wang, et al.
Published: (2019-02-01)

Effects of Short-Term Exenatide Treatment on Regional Fat Distribution, Glycated Hemoglobin Levels, and Aortic Pulse Wave Velocity of Obese Type 2 Diabetes Mellitus Patients
by: Ju-Young Hong, et al.
Published: (2016-03-01)

Incretin Mimetics in the Indian Context: Revisiting Exenatide
by: Shambo S Samajdar, et al.
Published: (2022-08-01)

Exenatide and Dapagliflozin Combination Enhances Sertoli Cell Secretion of Key Metabolites for Spermatogenesis
by: João C. Ribeiro, et al.
Published: (2022-05-01)

Comparison of exenatide alone or combined with metformin versus metformin in the treatment of polycystic ovaries: a systematic review and meta-analysis
by: Yan Hu, et al.
Published: (2023-11-01)

Efficacy of exenatide, ozone, and methyl prednisolone for the recovery of infraorbital nerve paresthesia after injury in rats
by: Mehdi Abrishami, et al.
Published: (2021-01-01)

Cumulative Evidence for the Association of Thrombosis and the Prognosis of COVID-19: Systematic Review and Meta-Analysis
by: Dongqiong Xiao, et al.
Published: (2022-01-01)

Effects of Exenatide on Coagulation and Platelet Aggregation in Patients with Type 2 Diabetes
by: Zhang Y, et al.
Published: (2021-07-01)

Comparison of the effects of twice-daily exenatide and insulin on carotid intima-media thickness in type 2 diabetes mellitus patients: a 52-week randomized, open-label, controlled trial
by: Jie Zhang, et al.
Published: (2020-04-01)

Rationally Designed Dendritic Silica Nanoparticles for Oral Delivery of Exenatide
by: Muhammad Mustafa Abeer, et al.
Published: (2019-08-01)

Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus
by: Kun-Ho Yoon, et al.
Published: (2017-12-01)

The Effects of pH and Excipients on Exenatide Stability in Solution
by: Alexander Benet, et al.
Published: (2021-08-01)

Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: Effect of exenatide
by: Vaghasiya Jitendra, et al.
Published: (2010-01-01)