Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut
Perforation is frequently observed among acute appendicitis patients, which characterized by high fever and increased leucocyte level. The aim of this study is to determine the accuracy of total leucocyte count (TLC) and symptom duration (SD) as predictors of perforation in acute appendicitis patien...
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| Format: | Article |
| Language: | English |
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Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa
2017-11-01
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| Series: | WMJ (Warmadewa Medical Journal) |
| Subjects: | |
| Online Access: | https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/446 |
| _version_ | 1797650796070830080 |
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| author | I Ketut Tangking Widarsa Cokorda Istri Padmi |
| author_facet | I Ketut Tangking Widarsa Cokorda Istri Padmi |
| author_sort | I Ketut Tangking Widarsa |
| collection | DOAJ |
| description | Perforation is frequently observed among acute appendicitis patients, which characterized by high fever and increased leucocyte level. The aim of this study is to determine the accuracy of total leucocyte count (TLC) and symptom duration (SD) as predictors of perforation in acute appendicitis patients. A retrospective cross sectional study was conducted and 96 acute appendicitis patients were enrolled in the study. The subjects were selected based on consecutive method taken from inpatient register of 2014 -2015 of Sanjiwani Hospital at Gianyar. Demographic data, SD and TLC were collected from medical record. Perforation was diagnosed based on the result of pathology and anatomy examinations. Chi square test and Poisson regression method were performed to analyze the association between TLC, SD and incidence of perforation. Positive predictive value (PPV) and Negative predictive value (NPV) were also calculated to measure the level of accuracy of the predictors. Results show that Relative Risk (RR) of TLC (>18.000/ml:≤18.000/ml) was 2.9 (1.2 – 6.7) whereas RR of SD (>24hours:≤24hours) was 2.3 (1.1 – 4.9). PPV/NPV of TLC, SD and TLC&SD combination were 59.4/93.8; 52.9/91.9; and 82.4/88.4, respectively. As conclusion, TLC&SD combined has high accuracy as predictor of perforation in acute appendicitis patients. |
| first_indexed | 2024-03-11T16:05:39Z |
| format | Article |
| id | doaj.art-f61796dc947e4c3986d9b06b05115b9e |
| institution | Directory Open Access Journal |
| issn | 2527-4627 2579-9010 |
| language | English |
| last_indexed | 2024-03-11T16:05:39Z |
| publishDate | 2017-11-01 |
| publisher | Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa |
| record_format | Article |
| series | WMJ (Warmadewa Medical Journal) |
| spelling | doaj.art-f61796dc947e4c3986d9b06b05115b9e2023-10-25T04:14:52ZengFakultas Kedokteran dan Ilmu Kesehatan, Universitas WarmadewaWMJ (Warmadewa Medical Journal)2527-46272579-90102017-11-01227176https://doi.org/10.22225/wmj.2.2.446.71-76Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut I Ketut Tangking Widarsa 0Cokorda Istri Padmi 1Department of Public Health, Faculty of Medicine and Health Scienses, Warmadewa University Department of Public Health, Faculty of Medicine and Health Scienses, Warmadewa University Perforation is frequently observed among acute appendicitis patients, which characterized by high fever and increased leucocyte level. The aim of this study is to determine the accuracy of total leucocyte count (TLC) and symptom duration (SD) as predictors of perforation in acute appendicitis patients. A retrospective cross sectional study was conducted and 96 acute appendicitis patients were enrolled in the study. The subjects were selected based on consecutive method taken from inpatient register of 2014 -2015 of Sanjiwani Hospital at Gianyar. Demographic data, SD and TLC were collected from medical record. Perforation was diagnosed based on the result of pathology and anatomy examinations. Chi square test and Poisson regression method were performed to analyze the association between TLC, SD and incidence of perforation. Positive predictive value (PPV) and Negative predictive value (NPV) were also calculated to measure the level of accuracy of the predictors. Results show that Relative Risk (RR) of TLC (>18.000/ml:≤18.000/ml) was 2.9 (1.2 – 6.7) whereas RR of SD (>24hours:≤24hours) was 2.3 (1.1 – 4.9). PPV/NPV of TLC, SD and TLC&SD combination were 59.4/93.8; 52.9/91.9; and 82.4/88.4, respectively. As conclusion, TLC&SD combined has high accuracy as predictor of perforation in acute appendicitis patients.https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/446apendisitis perforationtotal leucocyte counttime duration |
| spellingShingle | I Ketut Tangking Widarsa Cokorda Istri Padmi Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut WMJ (Warmadewa Medical Journal) apendisitis perforation total leucocyte count time duration |
| title | Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut |
| title_full | Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut |
| title_fullStr | Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut |
| title_full_unstemmed | Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut |
| title_short | Akurasi Total Hitung Leukosit dan Durasi Simtom sebagai Prediktor Perforasi Apendisitis pada Penderita Apendisitis Akut |
| title_sort | akurasi total hitung leukosit dan durasi simtom sebagai prediktor perforasi apendisitis pada penderita apendisitis akut |
| topic | apendisitis perforation total leucocyte count time duration |
| url | https://www.ejournal.warmadewa.ac.id/index.php/warmadewa_medical_journal/article/view/446 |
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