Serum d-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker

Serum d-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker

Abstract d-Serine acts as a co-agonist of N-methyl-d-aspartate receptors (NMDAR) which appear overactivated in AD, while d-aspartate is a modulatory molecule acting on NMDAR as a second agonist. The aim of this work is to clarify whether the levels of these d-amino acids in serum are deregulated in...

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Bibliographic Details
Main Authors: Luciano Piubelli, Loredano Pollegioni, Valentina Rabattoni, Marco Mauri, Lucia Princiotta Cariddi, Maurizio Versino, Silvia Sacchi
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01202-3

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