Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters

Abstract Background Borderline personality disorder (BPD) and history of prior suicide attempt (SA) have been shown to be high predictors for subsequent suicide. However, no previous study has examined how both factors interact to modify clinical and suicide severity among adolescents. Methods This...

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Main Authors: Aveline Aouidad, David Cohen, Bojan Mirkovic, Hugues Pellerin, Sébastien Garny de La Rivière, Angèle Consoli, Priscille Gérardin, Jean-Marc Guilé
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-020-02930-4
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author Aveline Aouidad
David Cohen
Bojan Mirkovic
Hugues Pellerin
Sébastien Garny de La Rivière
Angèle Consoli
Priscille Gérardin
Jean-Marc Guilé
author_facet Aveline Aouidad
David Cohen
Bojan Mirkovic
Hugues Pellerin
Sébastien Garny de La Rivière
Angèle Consoli
Priscille Gérardin
Jean-Marc Guilé
author_sort Aveline Aouidad
collection DOAJ
description Abstract Background Borderline personality disorder (BPD) and history of prior suicide attempt (SA) have been shown to be high predictors for subsequent suicide. However, no previous study has examined how both factors interact to modify clinical and suicide severity among adolescents. Methods This study presents a comprehensive assessment of 302 adolescents (265 girls, mean age = 14.7 years) hospitalized after a SA. To test clinical interactions between BPD and history of prior SA, the sample was divided into single attempters without BPD (non-BPD-SA, N = 80), single attempters with BPD (BPD-SA, N = 127) and multiple attempters with BPD (BPD-MA, N = 95). Results Univariate analyses revealed a severity gradient among the 3 groups with an additive effect of BPD on the clinical and suicide severity already conferred by a history of SA. This gradient encompassed categorical (anxiety and conduct disorders and non-suicidal-self-injury [NSSI]) and dimensional comorbidities (substance use and depression severity) and suicide characteristics (age at first SA). According to regression analyses, the BPD-MA group that was associated with the most severe clinical presentation also showed specific features: the first SA at a younger age and a higher prevalence of non-suicidal self-injury (NSSI) and anxiety disorders. The BPD-MA group was not associated with higher impulsivity or frequency of negative life events. Conclusions Based on these findings and to improve youth suicide prevention, future studies should systematically consider BPD and the efficacy of reinforcing early interventions for anxiety disorders and NSSI.
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spelling doaj.art-f626ddae6652471ab5577718a4657b042022-12-22T00:28:15ZengBMCBMC Psychiatry1471-244X2020-11-0120111310.1186/s12888-020-02930-4Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attemptersAveline Aouidad0David Cohen1Bojan Mirkovic2Hugues Pellerin3Sébastien Garny de La Rivière4Angèle Consoli5Priscille Gérardin6Jean-Marc Guilé7Hopital Universitaire Pitie SalpetriereInstitut des Systemes Intelligents et de RobotiqueHopital Charles NicolleHopital Universitaire Pitie SalpetriereCentre Hospitalier Universitaire Amiens-PicardieHopital Universitaire Pitie SalpetriereHopital Charles NicolleCentre Hospitalier Universitaire Amiens-PicardieAbstract Background Borderline personality disorder (BPD) and history of prior suicide attempt (SA) have been shown to be high predictors for subsequent suicide. However, no previous study has examined how both factors interact to modify clinical and suicide severity among adolescents. Methods This study presents a comprehensive assessment of 302 adolescents (265 girls, mean age = 14.7 years) hospitalized after a SA. To test clinical interactions between BPD and history of prior SA, the sample was divided into single attempters without BPD (non-BPD-SA, N = 80), single attempters with BPD (BPD-SA, N = 127) and multiple attempters with BPD (BPD-MA, N = 95). Results Univariate analyses revealed a severity gradient among the 3 groups with an additive effect of BPD on the clinical and suicide severity already conferred by a history of SA. This gradient encompassed categorical (anxiety and conduct disorders and non-suicidal-self-injury [NSSI]) and dimensional comorbidities (substance use and depression severity) and suicide characteristics (age at first SA). According to regression analyses, the BPD-MA group that was associated with the most severe clinical presentation also showed specific features: the first SA at a younger age and a higher prevalence of non-suicidal self-injury (NSSI) and anxiety disorders. The BPD-MA group was not associated with higher impulsivity or frequency of negative life events. Conclusions Based on these findings and to improve youth suicide prevention, future studies should systematically consider BPD and the efficacy of reinforcing early interventions for anxiety disorders and NSSI.http://link.springer.com/article/10.1186/s12888-020-02930-4Borderline personality disorderSuicide attemptAdolescentsAnxiety disorderNon-suicidal self-injuryInpatients
spellingShingle Aveline Aouidad
David Cohen
Bojan Mirkovic
Hugues Pellerin
Sébastien Garny de La Rivière
Angèle Consoli
Priscille Gérardin
Jean-Marc Guilé
Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
BMC Psychiatry
Borderline personality disorder
Suicide attempt
Adolescents
Anxiety disorder
Non-suicidal self-injury
Inpatients
title Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
title_full Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
title_fullStr Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
title_full_unstemmed Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
title_short Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
title_sort borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters
topic Borderline personality disorder
Suicide attempt
Adolescents
Anxiety disorder
Non-suicidal self-injury
Inpatients
url http://link.springer.com/article/10.1186/s12888-020-02930-4
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