The Myelin Water Fraction Serves as a Marker for Age-Related Myelin Alterations in the Cerebral White Matter – A Multiparametric MRI Aging Study

The Myelin Water Fraction Serves as a Marker for Age-Related Myelin Alterations in the Cerebral White Matter – A Multiparametric MRI Aging Study

Quantitative MRI modalities, such as diffusion tensor imaging (DTI) or magnetization transfer imaging (MTI) are sensitive to the neuronal effects of aging of the cerebral white matter (WM), but lack the specificity for myelin content. Myelin water imaging (MWI) is highly specific for myelin and may...

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Bibliographic Details
Main Authors: Tobias D. Faizy, Christian Thaler, Gabriel Broocks, Fabian Flottmann, Hannes Leischner, Helge Kniep, Jawed Nawabi, Gerhard Schön, Jan-Patrick Stellmann, André Kemmling, Ravinder Reddy, Jeremy J. Heit, Jens Fiehler, Dushyant Kumar, Uta Hanning
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Neuroscience
Subjects:
T2-relaxometry
myelin water imaging
diffusion imaging
magnetization transfer imaging
normal aging
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00136/full

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