Cervical Cancer Neoantigen Landscape and Immune Activity is Associated with Human Papillomavirus Master Regulators

Cervical Cancer Neoantigen Landscape and Immune Activity is Associated with Human Papillomavirus Master Regulators

Human papillomaviruses (HPVs) play a major role in development of cervical cancer, and HPV oncoproteins are being targeted by immunotherapies. Although these treatments show promising results in the clinic, many patients do not benefit or the durability is limited. In addition to HPV antigens, neoan...

Full description

Bibliographic Details
Main Authors: Yong Qin, Suhendan Ekmekcioglu, Marie-Andrée Forget, Lorant Szekvolgyi, Patrick Hwu, Elizabeth A. Grimm, Amir A. Jazaeri, Jason Roszik
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
cervical cancer
neoantigens
human papillomavirus
master regulators
immunotherapy
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00689/full

Similar Items

Similar Items