Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells

Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells

Objective (s):Hyperglycemia is widely recognized as the underlying cause for some debilitating conditions in diabetic patients. The role of cannabinoid CB1 and vanilloid TRPV1 receptors and their endogenous agonists, endovanilloids, in diabetic neuropathy is shown in many studies. Here we have used...

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Bibliographic Details
Main Authors: Ahmad Mohammadi-Farani, Mahmoud Ghazi-Khansari, Mousa Sahebgharani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
CB1
Hyperglycemia
PC12 cells
TRPV1
Online Access:http://ijbms.mums.ac.ir/pdf_3330_e5427803224aac94aa5d4ea62f5b89c8.html

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