The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study

As a component of traditional Chinese medicine (TCM), acupuncture has the potential to lower blood pressure (BP) in patients with hypertension. Emerging evidence indicates that the acupuncture-induced inhibition of high BP occurs through the activation of the pathway in the afferent, central, and ef...

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Main Authors: Hao Fan, Jing-Wen Yang, Li-Qiong Wang, Jin Huang, Lu-Lu Lin, Yu Wang, Na Zhang, Cun-Zhi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00138/full
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author Hao Fan
Hao Fan
Jing-Wen Yang
Li-Qiong Wang
Jin Huang
Lu-Lu Lin
Yu Wang
Na Zhang
Cun-Zhi Liu
author_facet Hao Fan
Hao Fan
Jing-Wen Yang
Li-Qiong Wang
Jin Huang
Lu-Lu Lin
Yu Wang
Na Zhang
Cun-Zhi Liu
author_sort Hao Fan
collection DOAJ
description As a component of traditional Chinese medicine (TCM), acupuncture has the potential to lower blood pressure (BP) in patients with hypertension. Emerging evidence indicates that the acupuncture-induced inhibition of high BP occurs through the activation of the pathway in the afferent, central, and efferent pathways. An increasing number of studies have demonstrated that acupuncture not only activates distinct brain regions under conditions of hypertension caused by an imbalance between the sympathetic and parasympathetic systems but also modulates neurotransmitters in related brain regions to alleviate the autonomic response. The activity of these pathways can be assessed by injecting agonists or inhibitors or by performing neurotomy. This review focuses on the clinical and mechanistic studies of acupuncture in modulating BP, which might provide a neurobiological foundation for the effects of acupuncture. Although many mechanisms underlying the effects of acupuncture on cardiovascular function have been identified, further investigation is warranted.
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spelling doaj.art-f63b366a3df8400b880023c1f92056d62022-12-22T01:33:58ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652020-05-011210.3389/fnagi.2020.00138522200The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic StudyHao Fan0Hao Fan1Jing-Wen Yang2Li-Qiong Wang3Jin Huang4Lu-Lu Lin5Yu Wang6Na Zhang7Cun-Zhi Liu8Acupuncture Research Center, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, ChinaAcupuncture Research Center, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaAcupuncture Research Center, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, ChinaAcupuncture Research Center, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaDepartment of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, ChinaSchool of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, ChinaAcupuncture Research Center, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaAs a component of traditional Chinese medicine (TCM), acupuncture has the potential to lower blood pressure (BP) in patients with hypertension. Emerging evidence indicates that the acupuncture-induced inhibition of high BP occurs through the activation of the pathway in the afferent, central, and efferent pathways. An increasing number of studies have demonstrated that acupuncture not only activates distinct brain regions under conditions of hypertension caused by an imbalance between the sympathetic and parasympathetic systems but also modulates neurotransmitters in related brain regions to alleviate the autonomic response. The activity of these pathways can be assessed by injecting agonists or inhibitors or by performing neurotomy. This review focuses on the clinical and mechanistic studies of acupuncture in modulating BP, which might provide a neurobiological foundation for the effects of acupuncture. Although many mechanisms underlying the effects of acupuncture on cardiovascular function have been identified, further investigation is warranted.https://www.frontiersin.org/article/10.3389/fnagi.2020.00138/fullacupunctureblood pressureclinical studyhypertensionmechanism study
spellingShingle Hao Fan
Hao Fan
Jing-Wen Yang
Li-Qiong Wang
Jin Huang
Lu-Lu Lin
Yu Wang
Na Zhang
Cun-Zhi Liu
The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
Frontiers in Aging Neuroscience
acupuncture
blood pressure
clinical study
hypertension
mechanism study
title The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
title_full The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
title_fullStr The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
title_full_unstemmed The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
title_short The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study
title_sort hypotensive role of acupuncture in hypertension clinical study and mechanistic study
topic acupuncture
blood pressure
clinical study
hypertension
mechanism study
url https://www.frontiersin.org/article/10.3389/fnagi.2020.00138/full
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