Emergence of Treadmill Running Ability and Quantitative Assessment of Gait Dynamics in Young Ts65Dn Mice: A Mouse Model for Down Syndrome

Emergence of Treadmill Running Ability and Quantitative Assessment of Gait Dynamics in Young Ts65Dn Mice: A Mouse Model for Down Syndrome

Down syndrome (DS), which results from the complete or partial trisomy of chromosome 21 (trisomy-21), is the most common genetically defined cause of intellectual disability. Trisomy-21 also produces, or is associated with, many neurodevelopmental phenotypes and neurological comorbidities, including...

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Bibliographic Details
Main Authors: Jonah J. Scott-McKean, Ryan Jones, Mark W. Johnson, Joyce Mier, Ines A. Basten, Melissa R. Stasko, Alberto C. S. Costa
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Brain Sciences
Subjects:
down syndrome
trisomy 21
Ts65Dn mouse
neurodevelopment
balance
motor control
Online Access:https://www.mdpi.com/2076-3425/13/5/743

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