Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach

Introduction: Quantile regression is a valuable alternative for survival data analysis, enabling flexible evaluations of covariate effects on survival outcomes with intuitive interpretations. It offers practical computation and reliability. However, challenges arise when applying quantile regressio...

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Main Authors: Fereshteh Mokhtarpour, Mostafa Hosseini, Akram Yazdani, Mehdi Yaseri
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2023-06-01
Series:Journal of Biostatistics and Epidemiology
Subjects:
Online Access:https://jbe.tums.ac.ir/index.php/jbe/article/view/1271
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author Fereshteh Mokhtarpour
Mostafa Hosseini
Akram Yazdani
Mehdi Yaseri
author_facet Fereshteh Mokhtarpour
Mostafa Hosseini
Akram Yazdani
Mehdi Yaseri
author_sort Fereshteh Mokhtarpour
collection DOAJ
description Introduction: Quantile regression is a valuable alternative for survival data analysis, enabling flexible evaluations of covariate effects on survival outcomes with intuitive interpretations. It offers practical computation and reliability. However, challenges arise when applying quantile regression to censored data, particularly for upper quantiles. The minimum distance approach, utilizing dual-kernel estimation and the inverse cumulative distribution function, shows promise in addressing these challenges, especially with Methods: This study contrasts two methods within the realm of quantile linear regression for survival analysis: check-based modeling and the minimum distance approach. Effectiveness is assessed across various scenarios through comprehensive simulation. Results: The simulation results showed that using the quantile regression model with the minimum distance approach reduces the percentage of root mean square error in parameter estimation compared to the quantile regression models based on the check loss function. Additionally, a larger sample size and reduced censoring percentage led to decreased root mean square error in parameter estimation. Conclusion: The research highlights the benefits of using the minimum distance approach for quantile regression. It reduces errors, improves model predictions, captures patterns, and optimizes parameters even with complete data. However, this approach has limitations. The accuracy of estimated quantiles can be influenced by the choice of distance metric and weighting scheme. The assumption of independence between censoring mechanism and survival time may not hold in real-world scenarios. Additionally, dealing with large datasets can be computationally complex.
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spelling doaj.art-f647b05be9854efcac90588861dffe472024-02-18T04:06:24ZengTehran University of Medical SciencesJournal of Biostatistics and Epidemiology2383-41962383-420X2023-06-019210.18502/jbe.v9i2.14629Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance ApproachFereshteh Mokhtarpour0Mostafa Hosseini1Akram Yazdani2Mehdi Yaseri3Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Biostatistics and Epidemiology, Faculty of Health, Kashan University of Medical Sciences, Kashan, IranDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Introduction: Quantile regression is a valuable alternative for survival data analysis, enabling flexible evaluations of covariate effects on survival outcomes with intuitive interpretations. It offers practical computation and reliability. However, challenges arise when applying quantile regression to censored data, particularly for upper quantiles. The minimum distance approach, utilizing dual-kernel estimation and the inverse cumulative distribution function, shows promise in addressing these challenges, especially with Methods: This study contrasts two methods within the realm of quantile linear regression for survival analysis: check-based modeling and the minimum distance approach. Effectiveness is assessed across various scenarios through comprehensive simulation. Results: The simulation results showed that using the quantile regression model with the minimum distance approach reduces the percentage of root mean square error in parameter estimation compared to the quantile regression models based on the check loss function. Additionally, a larger sample size and reduced censoring percentage led to decreased root mean square error in parameter estimation. Conclusion: The research highlights the benefits of using the minimum distance approach for quantile regression. It reduces errors, improves model predictions, captures patterns, and optimizes parameters even with complete data. However, this approach has limitations. The accuracy of estimated quantiles can be influenced by the choice of distance metric and weighting scheme. The assumption of independence between censoring mechanism and survival time may not hold in real-world scenarios. Additionally, dealing with large datasets can be computationally complex. https://jbe.tums.ac.ir/index.php/jbe/article/view/1271Quantile RegressionMinimum distance approachSurvivalCheck-based modelingInverse cumulative distribution function
spellingShingle Fereshteh Mokhtarpour
Mostafa Hosseini
Akram Yazdani
Mehdi Yaseri
Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
Journal of Biostatistics and Epidemiology
Quantile Regression
Minimum distance approach
Survival
Check-based modeling
Inverse cumulative distribution function
title Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
title_full Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
title_fullStr Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
title_full_unstemmed Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
title_short Quantile Regression in Survival Analysis: Comparing Check-Based Modeling and the Minimum Distance Approach
title_sort quantile regression in survival analysis comparing check based modeling and the minimum distance approach
topic Quantile Regression
Minimum distance approach
Survival
Check-based modeling
Inverse cumulative distribution function
url https://jbe.tums.ac.ir/index.php/jbe/article/view/1271
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