An agent-based model of monocyte differentiation into tumour-associated macrophages in chronic lymphocytic leukemia
Summary: Monocyte-derived macrophages help maintain tissue homeostasis and defend the organism against pathogens. In tumors, recent studies have uncovered complex macrophage populations, including tumor-associated macrophages, which support tumorigenesis through cancer hallmarks such as immunosuppre...
Main Authors: | Nina Verstraete, Malvina Marku, Marcin Domagala, Hélène Arduin, Julie Bordenave, Jean-Jacques Fournié, Loïc Ysebaert, Mary Poupot, Vera Pancaldi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223009744 |
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