Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database
Abstract Background Impaired kidney function is the hallmark of chronic kidney disease (CKD), and is associated with increased risk of all-cause mortality in the elderly. In the present cross-sectional population-based study, we aimed to evaluate the associations between lifestyle factors (exercise...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | BMC Nephrology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12882-020-01838-1 |
| _version_ | 1818029646216691712 |
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| author | Horng-Jinh Chang Kuan-Reng Lin Meng-Te Lin Junn-Liang Chang |
| author_facet | Horng-Jinh Chang Kuan-Reng Lin Meng-Te Lin Junn-Liang Chang |
| author_sort | Horng-Jinh Chang |
| collection | DOAJ |
| description | Abstract Background Impaired kidney function is the hallmark of chronic kidney disease (CKD), and is associated with increased risk of all-cause mortality in the elderly. In the present cross-sectional population-based study, we aimed to evaluate the associations between lifestyle factors (exercise habit, alcohol consumption, smoking history, and betel nut chewing) and decreased kidney function. Methods The data from the Taipei City Elderly Health Examination Database (2006 to 2012) were extracted. Associations between risk factors and reduced estimated Glomerular filtration rate (eGFR) were evaluated by regression and stratification analyses. Results A total of 297,603 participants were included in the final analysis, and 29.7% of them had reduced eGFR. Smoking was significantly associated with an elevated risk of reduced eGFR. While, physical exercise conferred to a significantly decreased adjusted odds ratio (aOR) in reduced eGFR (regular exercise, aOR = 0.79; occasional exercise, aOR = 0.87). Furthermore, the protective effect of exercise habit against reduced eGFR was not affected by comorbid conditions, such as hypertension, diabetes, obesity, and cardiovascular disease. Conclusions Engaging in physical exercise was beneficially associated with reduced eGFR in older individuals. Longitudinal or prospective studies are warranted for confirmation and extrapolation of the current findings. |
| first_indexed | 2024-12-10T05:23:00Z |
| format | Article |
| id | doaj.art-f649fee4eb0846d2baed375908e4a772 |
| institution | Directory Open Access Journal |
| issn | 1471-2369 |
| language | English |
| last_indexed | 2024-12-10T05:23:00Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Nephrology |
| spelling | doaj.art-f649fee4eb0846d2baed375908e4a7722022-12-22T02:00:46ZengBMCBMC Nephrology1471-23692020-05-0121111010.1186/s12882-020-01838-1Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination databaseHorng-Jinh Chang0Kuan-Reng Lin1Meng-Te Lin2Junn-Liang Chang3Department of Management Sciences, Tamkang UniversityDepartment of Management Sciences, Tamkang UniversityDepartment of Pathology & Laboratory Medicine, Taoyuan Armed Forces General HospitalDepartment of Pathology & Laboratory Medicine, Taoyuan Armed Forces General HospitalAbstract Background Impaired kidney function is the hallmark of chronic kidney disease (CKD), and is associated with increased risk of all-cause mortality in the elderly. In the present cross-sectional population-based study, we aimed to evaluate the associations between lifestyle factors (exercise habit, alcohol consumption, smoking history, and betel nut chewing) and decreased kidney function. Methods The data from the Taipei City Elderly Health Examination Database (2006 to 2012) were extracted. Associations between risk factors and reduced estimated Glomerular filtration rate (eGFR) were evaluated by regression and stratification analyses. Results A total of 297,603 participants were included in the final analysis, and 29.7% of them had reduced eGFR. Smoking was significantly associated with an elevated risk of reduced eGFR. While, physical exercise conferred to a significantly decreased adjusted odds ratio (aOR) in reduced eGFR (regular exercise, aOR = 0.79; occasional exercise, aOR = 0.87). Furthermore, the protective effect of exercise habit against reduced eGFR was not affected by comorbid conditions, such as hypertension, diabetes, obesity, and cardiovascular disease. Conclusions Engaging in physical exercise was beneficially associated with reduced eGFR in older individuals. Longitudinal or prospective studies are warranted for confirmation and extrapolation of the current findings.http://link.springer.com/article/10.1186/s12882-020-01838-1Kidney functionGlomerular filtration rateExerciseComorbidityRisk factor |
| spellingShingle | Horng-Jinh Chang Kuan-Reng Lin Meng-Te Lin Junn-Liang Chang Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database BMC Nephrology Kidney function Glomerular filtration rate Exercise Comorbidity Risk factor |
| title | Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database |
| title_full | Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database |
| title_fullStr | Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database |
| title_full_unstemmed | Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database |
| title_short | Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database |
| title_sort | association between lifestyle factors and decreased kidney function in older adults a community based cross sectional analysis of the taipei city elderly health examination database |
| topic | Kidney function Glomerular filtration rate Exercise Comorbidity Risk factor |
| url | http://link.springer.com/article/10.1186/s12882-020-01838-1 |
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