Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour
Background: HIV counselling and testing (HCT) clinics have the potential to be entry points for recruiting populations at high risk for HIV infection for HIV prevention and treatment studies. Cohort data from key populations are crucial for HIV study site selection. Method: This cohort study recruit...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-04-01
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| Series: | Journal of Virus Eradication |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2055664020304866 |
| _version_ | 1819093567094652928 |
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| author | Nittaya Phanuphak Robert Paris Donn Colby Suteeraporn Pinyakorn Mark de Souza Nipat Teeratakulpisarn Nitiya Chomchey Duanghathai Sutthichom Amornrat Sukjitpaiboonphol Tippawan Pankam Jerome H. Kim Jintanat Ananworanich Praphan Phanuphak |
| author_facet | Nittaya Phanuphak Robert Paris Donn Colby Suteeraporn Pinyakorn Mark de Souza Nipat Teeratakulpisarn Nitiya Chomchey Duanghathai Sutthichom Amornrat Sukjitpaiboonphol Tippawan Pankam Jerome H. Kim Jintanat Ananworanich Praphan Phanuphak |
| author_sort | Nittaya Phanuphak |
| collection | DOAJ |
| description | Background: HIV counselling and testing (HCT) clinics have the potential to be entry points for recruiting populations at high risk for HIV infection for HIV prevention and treatment studies. Cohort data from key populations are crucial for HIV study site selection. Method: This cohort study recruited clients at an HCT clinic in Bangkok, Thailand. HIV prevalence was assessed along with demographics, perception of risk and behavioural risk factors. Participants who were HIV negative at baseline were followed up every 4 months for up to 1 year to measure HIV incidence and changes in risk behaviour. Results: A total of 992 subjects enrolled; median age was 30 years, 27% were men who have sex with men (MSM) and 8% were commercial sex workers (CSW). Baseline HIV prevalence was 10%. Factors positively associated with HIV infection were age >30 years, lower educational status and being MSM. Factors negatively associated with HIV infection were self-perception of minimal or moderate risk. Overall dropout rate was 49%, with 24% not returning after enrolment. HIV incidence was lower than expected at 0.50 per 100 person-years overall and 1.95 per 100 person-years for MSM. Conclusions: This HCT population had a high baseline HIV prevalence but a low incidence rate on follow-up. Overall retention in the cohort was poor and may have resulted from suboptimal reminders and characteristics of high-risk clients who use anonymous HIV testing services. MSM had higher HIV incidence and better retention than other high-risk groups. |
| first_indexed | 2024-12-21T23:13:34Z |
| format | Article |
| id | doaj.art-f64bfe77e7eb4de48a0acab473661e06 |
| institution | Directory Open Access Journal |
| issn | 2055-6640 |
| language | English |
| last_indexed | 2024-12-21T23:13:34Z |
| publishDate | 2015-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Virus Eradication |
| spelling | doaj.art-f64bfe77e7eb4de48a0acab473661e062022-12-21T18:46:58ZengElsevierJournal of Virus Eradication2055-66402015-04-01127888Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviourNittaya Phanuphak0Robert Paris1Donn Colby2Suteeraporn Pinyakorn3Mark de Souza4Nipat Teeratakulpisarn5Nitiya Chomchey6Duanghathai Sutthichom7Amornrat Sukjitpaiboonphol8Tippawan Pankam9Jerome H. Kim10Jintanat Ananworanich11Praphan Phanuphak12SEARCH, Bangkok, Thailand; Thai Red Cross AIDS Research Centre, Bangkok, ThailandArmed Forces Research Institute of Medical Sciences, Bangkok, Thailand; US Military Malaria Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USACorresponding author: Donn Colby, Thai Red Cross AIDS Research Centre. 104 Rajdumri Road, Pathumwan, Bangkok, 10330, Thailand; SEARCH, Bangkok, Thailand; Thai Red Cross AIDS Research Centre, Bangkok, ThailandSEARCH, Bangkok, Thailand; Thai Red Cross AIDS Research Centre, Bangkok, ThailandSEARCH, Bangkok, Thailand; Thai Red Cross AIDS Research Centre, Bangkok, ThailandThai Red Cross AIDS Research Centre, Bangkok, ThailandSEARCH, Bangkok, ThailandSEARCH, Bangkok, ThailandThai Red Cross AIDS Research Centre, Bangkok, ThailandThai Red Cross AIDS Research Centre, Bangkok, ThailandUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring. MD, USASEARCH, Bangkok, Thailand; Thai Red Cross AIDS Research Centre, Bangkok, Thailand; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring. MD, USAThai Red Cross AIDS Research Centre, Bangkok, ThailandBackground: HIV counselling and testing (HCT) clinics have the potential to be entry points for recruiting populations at high risk for HIV infection for HIV prevention and treatment studies. Cohort data from key populations are crucial for HIV study site selection. Method: This cohort study recruited clients at an HCT clinic in Bangkok, Thailand. HIV prevalence was assessed along with demographics, perception of risk and behavioural risk factors. Participants who were HIV negative at baseline were followed up every 4 months for up to 1 year to measure HIV incidence and changes in risk behaviour. Results: A total of 992 subjects enrolled; median age was 30 years, 27% were men who have sex with men (MSM) and 8% were commercial sex workers (CSW). Baseline HIV prevalence was 10%. Factors positively associated with HIV infection were age >30 years, lower educational status and being MSM. Factors negatively associated with HIV infection were self-perception of minimal or moderate risk. Overall dropout rate was 49%, with 24% not returning after enrolment. HIV incidence was lower than expected at 0.50 per 100 person-years overall and 1.95 per 100 person-years for MSM. Conclusions: This HCT population had a high baseline HIV prevalence but a low incidence rate on follow-up. Overall retention in the cohort was poor and may have resulted from suboptimal reminders and characteristics of high-risk clients who use anonymous HIV testing services. MSM had higher HIV incidence and better retention than other high-risk groups.http://www.sciencedirect.com/science/article/pii/S2055664020304866HIVincidenceprevalenceThailandMSMcohort |
| spellingShingle | Nittaya Phanuphak Robert Paris Donn Colby Suteeraporn Pinyakorn Mark de Souza Nipat Teeratakulpisarn Nitiya Chomchey Duanghathai Sutthichom Amornrat Sukjitpaiboonphol Tippawan Pankam Jerome H. Kim Jintanat Ananworanich Praphan Phanuphak Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour Journal of Virus Eradication HIV incidence prevalence Thailand MSM cohort |
| title | Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour |
| title_full | Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour |
| title_fullStr | Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour |
| title_full_unstemmed | Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour |
| title_short | Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour |
| title_sort | low incidence of hiv infection in an anonymous hiv counselling and testing clinic cohort in bangkok thailand despite high hiv prevalence and self report of high risk behaviour |
| topic | HIV incidence prevalence Thailand MSM cohort |
| url | http://www.sciencedirect.com/science/article/pii/S2055664020304866 |
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