Efficient Delivery of Therapeutic siRNA by Fe<sub>3</sub>O<sub>4</sub> Magnetic Nanoparticles into Oral Cancer Cells

Efficient Delivery of Therapeutic siRNA by Fe<sub>3</sub>O<sub>4</sub> Magnetic Nanoparticles into Oral Cancer Cells

The incidence of oral cancer is increasing due to smoking, drinking, and human papillomavirus (HPV) infection, while the current treatments are not satisfactory. Small interfering RNA (siRNA)-based therapy has brought hope, but an efficient delivery system is still needed. Here, polyethyleneimine (P...

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Bibliographic Details
Main Authors: Lili Jin, Qiuyu Wang, Jiayu Chen, Zixiang Wang, Hongchuan Xin, Dianbao Zhang
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceutics
Subjects:
magnetic nanoparticle
iron oxide
sirna delivery
bcl2
birc5/survivin
oral cancer
Online Access:https://www.mdpi.com/1999-4923/11/11/615

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