Efficient gene knockout in goats using CRISPR/Cas9 system.

Efficient gene knockout in goats using CRISPR/Cas9 system.

The CRISPR/Cas9 system has been adapted as an efficient genome editing tool in laboratory animals such as mice, rats, zebrafish and pigs. Here, we report that CRISPR/Cas9 mediated approach can efficiently induce monoallelic and biallelic gene knockout in goat primary fibroblasts. Four genes were dis...

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Príomhchruthaitheoirí: Wei Ni, Jun Qiao, Shengwei Hu, Xinxia Zhao, Misha Regouski, Min Yang, Irina A Polejaeva, Chuangfu Chen
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2014-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC4154755?pdf=render

Ar líne

http://europepmc.org/articles/PMC4154755?pdf=render

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