Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation

Evidence on sex differences in the pathophysiology and interventional treatment of ventricular arrhythmia in ischemic (ICM) or non-ischemic cardiomyopathies (NICM) is limited. However, women have different etiologies and types of structural heart disease due to sex differences in genetics, proteo...

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Main Authors: Philipp Krisai, Ghassen Cheniti, Takamitsu Takagi, Tsukasa Kamakura, Elodie Surget, Clémentine André, Josselin Duchateau, Thomas Pambrun, Nicolas Derval, Frédéric Sacher, Pierre Jaïs, Michel Haïssaguerre, Mélèze Hocini
Format: Article
Language:English
Published: IMR Press 2022-01-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://article.imrpress.com/journal/RCM/23/1/10.31083/j.rcm2301014/2153-8174-23-1-014.pdf
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author Philipp Krisai
Ghassen Cheniti
Takamitsu Takagi
Tsukasa Kamakura
Elodie Surget
Clémentine André
Josselin Duchateau
Thomas Pambrun
Nicolas Derval
Frédéric Sacher
Pierre Jaïs
Michel Haïssaguerre
Mélèze Hocini
author_facet Philipp Krisai
Ghassen Cheniti
Takamitsu Takagi
Tsukasa Kamakura
Elodie Surget
Clémentine André
Josselin Duchateau
Thomas Pambrun
Nicolas Derval
Frédéric Sacher
Pierre Jaïs
Michel Haïssaguerre
Mélèze Hocini
author_sort Philipp Krisai
collection DOAJ
description Evidence on sex differences in the pathophysiology and interventional treatment of ventricular arrhythmia in ischemic (ICM) or non-ischemic cardiomyopathies (NICM) is limited. However, women have different etiologies and types of structural heart disease due to sex differences in genetics, proteomics and sex hormones. These differences may influence ventricular electrophysiological parameters and may require different treatment strategies. Considering that women were consistently under-represented in all randomized-controlled trials on VT ablation, the applicability of the study results to female patients is not known. In this article, we review the current knowledge and gaps in evidence about sex differences in the epidemiology, pathophysiology and catheter ablation in patients with ventricular arrhythmias.
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spelling doaj.art-f653bdabbf4446beab4d64de563718af2022-12-21T17:24:15ZengIMR PressReviews in Cardiovascular Medicine1530-65502022-01-0123101410.31083/j.rcm2301014S1530-6550(22)00301-5Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablationPhilipp Krisai0Ghassen Cheniti1Takamitsu Takagi2Tsukasa Kamakura3Elodie Surget4Clémentine André5Josselin Duchateau6Thomas Pambrun7Nicolas Derval8Frédéric Sacher9Pierre Jaïs10Michel Haïssaguerre11Mélèze Hocini12Electrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceElectrophysiology and Ablation Unit and LIRYC, 33600 CHU de Bordeaux, FranceEvidence on sex differences in the pathophysiology and interventional treatment of ventricular arrhythmia in ischemic (ICM) or non-ischemic cardiomyopathies (NICM) is limited. However, women have different etiologies and types of structural heart disease due to sex differences in genetics, proteomics and sex hormones. These differences may influence ventricular electrophysiological parameters and may require different treatment strategies. Considering that women were consistently under-represented in all randomized-controlled trials on VT ablation, the applicability of the study results to female patients is not known. In this article, we review the current knowledge and gaps in evidence about sex differences in the epidemiology, pathophysiology and catheter ablation in patients with ventricular arrhythmias.https://article.imrpress.com/journal/RCM/23/1/10.31083/j.rcm2301014/2153-8174-23-1-014.pdfventricular arrhythmiaventricular tachycardiacatheter ablationsex difference
spellingShingle Philipp Krisai
Ghassen Cheniti
Takamitsu Takagi
Tsukasa Kamakura
Elodie Surget
Clémentine André
Josselin Duchateau
Thomas Pambrun
Nicolas Derval
Frédéric Sacher
Pierre Jaïs
Michel Haïssaguerre
Mélèze Hocini
Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
Reviews in Cardiovascular Medicine
ventricular arrhythmia
ventricular tachycardia
catheter ablation
sex difference
title Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
title_full Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
title_fullStr Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
title_full_unstemmed Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
title_short Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
title_sort sex differences in ventricular arrhythmia epidemiology pathophysiology and catheter ablation
topic ventricular arrhythmia
ventricular tachycardia
catheter ablation
sex difference
url https://article.imrpress.com/journal/RCM/23/1/10.31083/j.rcm2301014/2153-8174-23-1-014.pdf
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