Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue

Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue

Objective(s): TLR-4 activates a number of inflammatory signaling pathways. Also, AMPK could be involved in anti-inflammatory signaling. The aim of this study was to identify whether stimulation of AMPK could inhibit LPS-induced Tlr-4 gene expression in mice hearts. Materials and methods: Heart AMPK...

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Bibliographic Details
Main Authors:	Maryam Rameshrad, Nasrin Maleki-Dizaji, Hamid Soraya, Negisa Seyed Toutounchi, Abolfazl Barzegari, Alireza Garjani
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2016-12-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	ACC A-769662 AMPK Compound-C Lipopolysaccharide TLR-4
Online Access:	http://ijbms.mums.ac.ir/article_7917_c6e102ce9fd836beabc0c3235560d57b.pdf

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