Estrogen suppresses SOX9 and activates markers of female development in a human testis-derived cell line
Abstract Background The increasing incidence of reproductive disorders in humans has been attributed to in utero exposure to estrogenic endocrine disruptors. In particular, exposure of the developing testis to exogenous estrogen can negatively impact male reproductive health. To determine how estrog...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-09-01
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Series: | BMC Molecular and Cell Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12860-020-00307-9 |