Impact of Quarantine and Vaccination Policies on Viral Load
Epidemics and pandemics are a field of scientific research since ancient times. The intensity of the repeated phenomena demonstrates their cyclicality in time. The ongoing COVID-19 pandemic, also known as the coronavirus pandemic, confirmed observations made in previous disease outbreaks. Epidemics...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/13/1/396 |
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| author | Dimitrios Koumatzidis Ioannis Seimenis Constantinos Loukas Theodoros Constantinidis Adam Adamopoulos |
| author_facet | Dimitrios Koumatzidis Ioannis Seimenis Constantinos Loukas Theodoros Constantinidis Adam Adamopoulos |
| author_sort | Dimitrios Koumatzidis |
| collection | DOAJ |
| description | Epidemics and pandemics are a field of scientific research since ancient times. The intensity of the repeated phenomena demonstrates their cyclicality in time. The ongoing COVID-19 pandemic, also known as the coronavirus pandemic, confirmed observations made in previous disease outbreaks. Epidemics are mainly characterized by two factors: (a) the population dynamics and (b) the nature of the disease. This article uses continuous mathematical models, on the basis of a scalable compartmental approach, characterized by systems of ordinary differential equations under the condition that individuals can freely move from one compartment to another. Numerous experiments were carried out to examine the impact of quarantine and vaccination policies, separately or in combination, on cumulative viral load, a measure adopted to reflect the cumulative viral burden of an infected population for a given time period. Current findings demonstrate that quarantine may play a crucial role in controlling an epidemic at its early stages, as well as the importance of early and widespread implementation of a vaccination program. The suggested approach may be utilized to study specific quarantine and vaccination scenarios, by manipulating various parameters such as the duration and extent of social distancing measures or the effectiveness and compliance to vaccination policies, and thus assist in decision making. |
| first_indexed | 2024-03-11T10:08:27Z |
| format | Article |
| id | doaj.art-f656ab4ac0e4423ea1d9f16f661bd21c |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-11T10:08:27Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-f656ab4ac0e4423ea1d9f16f661bd21c2023-11-16T14:56:29ZengMDPI AGApplied Sciences2076-34172022-12-0113139610.3390/app13010396Impact of Quarantine and Vaccination Policies on Viral LoadDimitrios Koumatzidis0Ioannis Seimenis1Constantinos Loukas2Theodoros Constantinidis3Adam Adamopoulos4Medical Physics Laboratory, Department of Medicine, Democritus University of Thrace, 68133 Alexandroupolis, GreeceMedical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceMedical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceMedical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceMedical Physics Laboratory, Department of Medicine, Democritus University of Thrace, 68133 Alexandroupolis, GreeceEpidemics and pandemics are a field of scientific research since ancient times. The intensity of the repeated phenomena demonstrates their cyclicality in time. The ongoing COVID-19 pandemic, also known as the coronavirus pandemic, confirmed observations made in previous disease outbreaks. Epidemics are mainly characterized by two factors: (a) the population dynamics and (b) the nature of the disease. This article uses continuous mathematical models, on the basis of a scalable compartmental approach, characterized by systems of ordinary differential equations under the condition that individuals can freely move from one compartment to another. Numerous experiments were carried out to examine the impact of quarantine and vaccination policies, separately or in combination, on cumulative viral load, a measure adopted to reflect the cumulative viral burden of an infected population for a given time period. Current findings demonstrate that quarantine may play a crucial role in controlling an epidemic at its early stages, as well as the importance of early and widespread implementation of a vaccination program. The suggested approach may be utilized to study specific quarantine and vaccination scenarios, by manipulating various parameters such as the duration and extent of social distancing measures or the effectiveness and compliance to vaccination policies, and thus assist in decision making.https://www.mdpi.com/2076-3417/13/1/396viral loadepidemicsepidemic policy |
| spellingShingle | Dimitrios Koumatzidis Ioannis Seimenis Constantinos Loukas Theodoros Constantinidis Adam Adamopoulos Impact of Quarantine and Vaccination Policies on Viral Load Applied Sciences viral load epidemics epidemic policy |
| title | Impact of Quarantine and Vaccination Policies on Viral Load |
| title_full | Impact of Quarantine and Vaccination Policies on Viral Load |
| title_fullStr | Impact of Quarantine and Vaccination Policies on Viral Load |
| title_full_unstemmed | Impact of Quarantine and Vaccination Policies on Viral Load |
| title_short | Impact of Quarantine and Vaccination Policies on Viral Load |
| title_sort | impact of quarantine and vaccination policies on viral load |
| topic | viral load epidemics epidemic policy |
| url | https://www.mdpi.com/2076-3417/13/1/396 |
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