Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing <i>Enterococcus faecalis</i> and <i>Staphylococcus aureus</i>

Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing <i>Enterococcus faecalis</i> and <i>Staphylococcus aureus</i>

The <i>optrA</i> gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of <i>optrA</i> and whether it involves antibiotic efflux or ribosom...

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Bibliographic Details
Main Authors: Yingyu Wang, Xiaowei Li, Yang Wang, Stefan Schwarz, Jianzhong Shen, Xi Xia
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
linezolid
florfenicol
<i>Enterococcus</i>
<i>Staphylococcus</i>
active efflux
ABC transporter
Online Access:https://www.mdpi.com/1420-3049/23/12/3195

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