Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy

Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy

Despite advances in its treatment, heart failure remains a major cause of morbidity and mortality, evidencing an urgent need for novel mechanism-based targets and strategies. Myocardial hypertrophy, caused by a wide variety of chronic stress stimuli, represents an independent risk factor for the dev...

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Bibliographic Details
Main Authors: David Aluja, Sara Delgado-Tomás, Marisol Ruiz-Meana, José A. Barrabés, Javier Inserte
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
calpain
calpastatin
myocardial hypertrophy
heart failure
Online Access:https://www.mdpi.com/1422-0067/23/8/4103

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