<b>Larvicidal activity of myricoidine from <i>Clerodendrum myricoides</i></b>

Chromatographic separation of a methanolic extract of <i>Clerodendrum myricoides</i> led to the isolation of myricoidine (<b>1</b>) whose structure was elucidated using IR, NMR and melting point. The crude fractions as well as <b>1</b> were subjected to larvicidal...

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Bibliographic Details
Main Authors: J.S. Kebenei, P.K. Ndalut, C.P. Kiprono
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2004-12-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:http://www.ajol.info/index.php/bcse/article/view/61456
Description
Summary:Chromatographic separation of a methanolic extract of <i>Clerodendrum myricoides</i> led to the isolation of myricoidine (<b>1</b>) whose structure was elucidated using IR, NMR and melting point. The crude fractions as well as <b>1</b> were subjected to larvicidal tests using the second instar larvae of <i>Anopheles gambiae</i> (malaria vector) at concentrations of 100, 75, 50, and 25 ppm. The crude extract and the compound were found to be active with LC<sub>50</sub> values of 14 and 9 ppm, respectively.
ISSN:1011-3924
1726-801X