SUMO modification and its regulation of signaling pathways
SUMO modification is a kind of post-translational modification of proteins, which plays an important role in regulating protein stability, protein-protein interaction and subcellular localization. SUMO modification of protein is the main mechanism for the formation of diabetes, tumors and other dise...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2021-04-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200419.pdf |
| _version_ | 1797365827434971136 |
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| author | XIAO Yun-fei, WANG Jia-bin, GENG Hai-gang, LIU Qing-juan |
| author_facet | XIAO Yun-fei, WANG Jia-bin, GENG Hai-gang, LIU Qing-juan |
| author_sort | XIAO Yun-fei, WANG Jia-bin, GENG Hai-gang, LIU Qing-juan |
| collection | DOAJ |
| description | SUMO modification is a kind of post-translational modification of proteins, which plays an important role in regulating protein stability, protein-protein interaction and subcellular localization. SUMO modification of protein is the main mechanism for the formation of diabetes, tumors and other diseases.It has become the key target for treatment. In this article, we have reviewed the latest advance in the relationship between protein SUMO modification and these pathways which are nuclear factor-κB (NF-κB) signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway and transforming growth factor-β (TGF-β). |
| first_indexed | 2024-03-08T16:54:29Z |
| format | Article |
| id | doaj.art-f65dac53c7464f9f8aab768ad66bc5ae |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:54:29Z |
| publishDate | 2021-04-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-f65dac53c7464f9f8aab768ad66bc5ae2024-01-05T03:04:57ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252021-04-01414578583SUMO modification and its regulation of signaling pathwaysXIAO Yun-fei, WANG Jia-bin, GENG Hai-gang, LIU Qing-juan0Key Laboratory of Nephrology of Hebei Province, Department of Pathology,College of Basic Medicine, Hebei Medical University, Shijiazhuang 050017,ChinaSUMO modification is a kind of post-translational modification of proteins, which plays an important role in regulating protein stability, protein-protein interaction and subcellular localization. SUMO modification of protein is the main mechanism for the formation of diabetes, tumors and other diseases.It has become the key target for treatment. In this article, we have reviewed the latest advance in the relationship between protein SUMO modification and these pathways which are nuclear factor-κB (NF-κB) signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway and transforming growth factor-β (TGF-β).http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200419.pdfsumo modification|nf-κb|mapk|tgf-β |
| spellingShingle | XIAO Yun-fei, WANG Jia-bin, GENG Hai-gang, LIU Qing-juan SUMO modification and its regulation of signaling pathways Jichu yixue yu linchuang sumo modification|nf-κb|mapk|tgf-β |
| title | SUMO modification and its regulation of signaling pathways |
| title_full | SUMO modification and its regulation of signaling pathways |
| title_fullStr | SUMO modification and its regulation of signaling pathways |
| title_full_unstemmed | SUMO modification and its regulation of signaling pathways |
| title_short | SUMO modification and its regulation of signaling pathways |
| title_sort | sumo modification and its regulation of signaling pathways |
| topic | sumo modification|nf-κb|mapk|tgf-β |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200419.pdf |
| work_keys_str_mv | AT xiaoyunfeiwangjiabingenghaigangliuqingjuan sumomodificationanditsregulationofsignalingpathways |