Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report

An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular exa...

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Main Authors: Jayanta Kumar Das, Jnanankar Medhi, Ranjay Chakravarty, Ronel Soibam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=3;spage=231;epage=233;aulast=Das
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author Jayanta Kumar Das
Jnanankar Medhi
Ranjay Chakravarty
Ronel Soibam
author_facet Jayanta Kumar Das
Jnanankar Medhi
Ranjay Chakravarty
Ronel Soibam
author_sort Jayanta Kumar Das
collection DOAJ
description An 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.
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spelling doaj.art-f65f3049387646778cf915375f75741c2022-12-21T18:20:51ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892011-01-0159323123310.4103/0301-4738.81039Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case reportJayanta Kumar DasJnanankar MedhiRanjay ChakravartyRonel SoibamAn 18-year-old woman was referred with late sequelae of chloroquine-induced Steven-Johnson syndrome. At the time of presentation, the symblepharon was involving the upper lids to almost the whole of the cornea, and part of the lower bulbar conjunctiva with the lower lid bilaterally. Other ocular examinations were not possible due to the symblepharon. B-scan ultrasonography revealed acoustically clear vitreous, normal chorioretinal thickness, and normal optic nerve head, with an attached retina. Conjunctivo-corneal adhesion released by superficial lamellar dissection of the cornea. Ocular surface reconstruction was carried out with a buccal mucous membrane. A bandage contact lens was placed over the cornea followed by the symblepharon ring to prevent further adhesion. The mucosal graft was well taken up along with corneal re-epithelization. Best corrected visual acuity of 20/120 in both sides after 1 month and 20/80 after 3 months was achieved and maintained till the 2.5-year follow-up.http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=3;spage=231;epage=233;aulast=DasAhmed glaucoma valvehypotonypost-penetrating-keratoplasty glaucomatube extrusionscleral patchRanibizumabbevacizumabchoroidal neovascular membraneage-related macular degenerationintravitreal injectioncentral macular thicknessbest corrected visual acuityIntravitreal injectionmethotrexatepharmacokineticsContrast sensitivitydiabetesglarepupil cycle timeAnemiadiabetic retinopathymicroalbuminuriaseverityObjective Structured Clinical ExaminationophthalmologyundergraduateAnisometropiaanisometropic amblyopiafusionstereopsisTraumatic cataractBirmingham Eye Trauma Terminology SystemIndiacataract surgeryChildren with learning disabilityocular disordersrefractive errorsspecial needsCharles Bonnet syndromedementiahallucinationspregabalinOcular surface reconstructionSteven-Johnson syndromesuperficial keratectomy
spellingShingle Jayanta Kumar Das
Jnanankar Medhi
Ranjay Chakravarty
Ronel Soibam
Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
Indian Journal of Ophthalmology
Ahmed glaucoma valve
hypotony
post-penetrating-keratoplasty glaucoma
tube extrusion
scleral patch
Ranibizumab
bevacizumab
choroidal neovascular membrane
age-related macular degeneration
intravitreal injection
central macular thickness
best corrected visual acuity
Intravitreal injection
methotrexate
pharmacokinetics
Contrast sensitivity
diabetes
glare
pupil cycle time
Anemia
diabetic retinopathy
microalbuminuria
severity
Objective Structured Clinical Examination
ophthalmology
undergraduate
Anisometropia
anisometropic amblyopia
fusion
stereopsis
Traumatic cataract
Birmingham Eye Trauma Terminology System
India
cataract surgery
Children with learning disability
ocular disorders
refractive errors
special needs
Charles Bonnet syndrome
dementia
hallucinations
pregabalin
Ocular surface reconstruction
Steven-Johnson syndrome
superficial keratectomy
title Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
title_full Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
title_fullStr Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
title_full_unstemmed Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
title_short Mucous membrane grafting for the post-Steven-Johnson syndrome symblepharon: A case report
title_sort mucous membrane grafting for the post steven johnson syndrome symblepharon a case report
topic Ahmed glaucoma valve
hypotony
post-penetrating-keratoplasty glaucoma
tube extrusion
scleral patch
Ranibizumab
bevacizumab
choroidal neovascular membrane
age-related macular degeneration
intravitreal injection
central macular thickness
best corrected visual acuity
Intravitreal injection
methotrexate
pharmacokinetics
Contrast sensitivity
diabetes
glare
pupil cycle time
Anemia
diabetic retinopathy
microalbuminuria
severity
Objective Structured Clinical Examination
ophthalmology
undergraduate
Anisometropia
anisometropic amblyopia
fusion
stereopsis
Traumatic cataract
Birmingham Eye Trauma Terminology System
India
cataract surgery
Children with learning disability
ocular disorders
refractive errors
special needs
Charles Bonnet syndrome
dementia
hallucinations
pregabalin
Ocular surface reconstruction
Steven-Johnson syndrome
superficial keratectomy
url http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=3;spage=231;epage=233;aulast=Das
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AT jnanankarmedhi mucousmembranegraftingforthepoststevenjohnsonsyndromesymblepharonacasereport
AT ranjaychakravarty mucousmembranegraftingforthepoststevenjohnsonsyndromesymblepharonacasereport
AT ronelsoibam mucousmembranegraftingforthepoststevenjohnsonsyndromesymblepharonacasereport