Telocytes in the urinary system
<p>Abstract</p> <p>Background</p> <p>Telocytes, a new type of interstitial cells, have been identified in many organs in mammals. The present studies aimed at investigating the ultrastructure, distribution and interactions of telocytes with surrounding cells in the urin...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-09-01
|
Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://www.translational-medicine.com/content/10/1/188 |
_version_ | 1818556352817004544 |
---|---|
author | Zheng Yonghua Zhu Tongyu Lin Miao Wu Duojiao Wang Xiangdong |
author_facet | Zheng Yonghua Zhu Tongyu Lin Miao Wu Duojiao Wang Xiangdong |
author_sort | Zheng Yonghua |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Telocytes, a new type of interstitial cells, have been identified in many organs in mammals. The present studies aimed at investigating the ultrastructure, distribution and interactions of telocytes with surrounding cells in the urinary system of rats, to confirm the existence of telocytes in kidneys, ureter and urinary bladder.</p> <p>Methods</p> <p>Samples of kidney, ureter, or urinary bladder were harvested for the ultrastructure by the electron microscope. The primary culture of telocytes was performed to investigate the dynamic alterations.</p> <p>Results</p> <p>Telocytes mainly located in the sub-capsular space of kidney, or between smooth muscle bundles and in the lamina propria of ureter and urinary bladder. Telocytes established numerous contacts with macrophages in the sub-capsular space of kidney, or with smooth muscle cells, nerve endings as well as blood capillaries in the ureter and urinary bladder. The complete morphology of telocytes with telopodes was observed clearly through the primary cell culture from the kidney tissues of rats.</p> <p>Conclusions</p> <p>Our data evidenced the existence of telocytes in the urinary system, which may contribute to the tissue reparation and regeneration.</p> |
first_indexed | 2024-12-13T23:46:15Z |
format | Article |
id | doaj.art-f66158dbdf1044c5b2b055f42a30d3ce |
institution | Directory Open Access Journal |
issn | 1479-5876 |
language | English |
last_indexed | 2024-12-13T23:46:15Z |
publishDate | 2012-09-01 |
publisher | BMC |
record_format | Article |
series | Journal of Translational Medicine |
spelling | doaj.art-f66158dbdf1044c5b2b055f42a30d3ce2022-12-21T23:26:57ZengBMCJournal of Translational Medicine1479-58762012-09-0110118810.1186/1479-5876-10-188Telocytes in the urinary systemZheng YonghuaZhu TongyuLin MiaoWu DuojiaoWang Xiangdong<p>Abstract</p> <p>Background</p> <p>Telocytes, a new type of interstitial cells, have been identified in many organs in mammals. The present studies aimed at investigating the ultrastructure, distribution and interactions of telocytes with surrounding cells in the urinary system of rats, to confirm the existence of telocytes in kidneys, ureter and urinary bladder.</p> <p>Methods</p> <p>Samples of kidney, ureter, or urinary bladder were harvested for the ultrastructure by the electron microscope. The primary culture of telocytes was performed to investigate the dynamic alterations.</p> <p>Results</p> <p>Telocytes mainly located in the sub-capsular space of kidney, or between smooth muscle bundles and in the lamina propria of ureter and urinary bladder. Telocytes established numerous contacts with macrophages in the sub-capsular space of kidney, or with smooth muscle cells, nerve endings as well as blood capillaries in the ureter and urinary bladder. The complete morphology of telocytes with telopodes was observed clearly through the primary cell culture from the kidney tissues of rats.</p> <p>Conclusions</p> <p>Our data evidenced the existence of telocytes in the urinary system, which may contribute to the tissue reparation and regeneration.</p>http://www.translational-medicine.com/content/10/1/188TelocytesKidneyUreterUrinary bladder |
spellingShingle | Zheng Yonghua Zhu Tongyu Lin Miao Wu Duojiao Wang Xiangdong Telocytes in the urinary system Journal of Translational Medicine Telocytes Kidney Ureter Urinary bladder |
title | Telocytes in the urinary system |
title_full | Telocytes in the urinary system |
title_fullStr | Telocytes in the urinary system |
title_full_unstemmed | Telocytes in the urinary system |
title_short | Telocytes in the urinary system |
title_sort | telocytes in the urinary system |
topic | Telocytes Kidney Ureter Urinary bladder |
url | http://www.translational-medicine.com/content/10/1/188 |
work_keys_str_mv | AT zhengyonghua telocytesintheurinarysystem AT zhutongyu telocytesintheurinarysystem AT linmiao telocytesintheurinarysystem AT wuduojiao telocytesintheurinarysystem AT wangxiangdong telocytesintheurinarysystem |