Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics
Epidemiological studies show that a high calcium intake reduces the risk of colon cancer. The objective was to study the association between calcium intake and colorectal neoplasia in a clinic-based sample of Hispanics adults from Puerto Rico. As part of this cross-sectional study, a total of 433 su...
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| Format: | Article |
| Language: | English |
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Sociedad Latinoamericana de Nutrición
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| Series: | Archivos Latinoamericanos de Nutrición |
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| Online Access: | http://www.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0004-06222010000400005&lng=en&tlng=en |
| _version_ | 1797968451539566592 |
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| author | Cristina Palacios Maritza Lopez Ana Patricia Ortiz Marcia Cruz Correa |
| author_facet | Cristina Palacios Maritza Lopez Ana Patricia Ortiz Marcia Cruz Correa |
| author_sort | Cristina Palacios |
| collection | DOAJ |
| description | Epidemiological studies show that a high calcium intake reduces the risk of colon cancer. The objective was to study the association between calcium intake and colorectal neoplasia in a clinic-based sample of Hispanics adults from Puerto Rico. As part of this cross-sectional study, a total of 433 subjects were recruited from surgery and gastroenterology clinics at the University of Puerto Rico. Calcium intake was estimated using a food frequency questionnaire (FFQ) of calcium rich foods. Socio-demographics, health history and colonoscopy results were obtained from the primary study. Chi square and odds ratios (OR) for colorectal neoplasia (adenomas and/or adenocarcinoma) were calculated for total calcium, dietary calcium and for calcium supplement use. In total, 312 (72%) from 433 participants completed the FFQ and had available colonoscopy results; from these, 196 (62.5%) were free of neoplasia and 117 (37.5%) had colorectal neoplasia. Colorectal neoplasia subjects were older, a lower proportion were females and less educated than those without neoplasia (p<0.01). Total calcium intake (median 1180 mg/d) was greater in those free of neoplasia compared to colorectal neoplasia subjects (median 1036 mg/d; p<0.05). A high total calcium intake and the use of calcium supplements significantly reduced the OR (crude and age adjusted) for colorectal neoplasia; although these associations lost statistical significance after additionally adjusting for gender and educational level. In conclusion, a high calcium intake and the use of calcium supplements may be protective against colorectal neoplasia, although a greater sample may be required to observe significant associations in a multivariate model. |
| first_indexed | 2024-04-11T02:47:07Z |
| format | Article |
| id | doaj.art-f667f587a2d14467bea6895d7e92182c |
| institution | Directory Open Access Journal |
| issn | 0004-0622 |
| language | English |
| last_indexed | 2024-04-11T02:47:07Z |
| publisher | Sociedad Latinoamericana de Nutrición |
| record_format | Article |
| series | Archivos Latinoamericanos de Nutrición |
| spelling | doaj.art-f667f587a2d14467bea6895d7e92182c2023-01-02T17:48:27ZengSociedad Latinoamericana de NutriciónArchivos Latinoamericanos de Nutrición0004-0622604348354S0004-06222010000400005Association between calcium intake and colorectal neoplasia in Puerto Rican HispanicsCristina PalaciosMaritza LopezAna Patricia OrtizMarcia Cruz CorreaEpidemiological studies show that a high calcium intake reduces the risk of colon cancer. The objective was to study the association between calcium intake and colorectal neoplasia in a clinic-based sample of Hispanics adults from Puerto Rico. As part of this cross-sectional study, a total of 433 subjects were recruited from surgery and gastroenterology clinics at the University of Puerto Rico. Calcium intake was estimated using a food frequency questionnaire (FFQ) of calcium rich foods. Socio-demographics, health history and colonoscopy results were obtained from the primary study. Chi square and odds ratios (OR) for colorectal neoplasia (adenomas and/or adenocarcinoma) were calculated for total calcium, dietary calcium and for calcium supplement use. In total, 312 (72%) from 433 participants completed the FFQ and had available colonoscopy results; from these, 196 (62.5%) were free of neoplasia and 117 (37.5%) had colorectal neoplasia. Colorectal neoplasia subjects were older, a lower proportion were females and less educated than those without neoplasia (p<0.01). Total calcium intake (median 1180 mg/d) was greater in those free of neoplasia compared to colorectal neoplasia subjects (median 1036 mg/d; p<0.05). A high total calcium intake and the use of calcium supplements significantly reduced the OR (crude and age adjusted) for colorectal neoplasia; although these associations lost statistical significance after additionally adjusting for gender and educational level. In conclusion, a high calcium intake and the use of calcium supplements may be protective against colorectal neoplasia, although a greater sample may be required to observe significant associations in a multivariate model.http://www.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0004-06222010000400005&lng=en&tlng=encalcium intakedietary calciumcalcium supplementsadenomascolorectal neoplasia |
| spellingShingle | Cristina Palacios Maritza Lopez Ana Patricia Ortiz Marcia Cruz Correa Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics Archivos Latinoamericanos de Nutrición calcium intake dietary calcium calcium supplements adenomas colorectal neoplasia |
| title | Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics |
| title_full | Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics |
| title_fullStr | Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics |
| title_full_unstemmed | Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics |
| title_short | Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics |
| title_sort | association between calcium intake and colorectal neoplasia in puerto rican hispanics |
| topic | calcium intake dietary calcium calcium supplements adenomas colorectal neoplasia |
| url | http://www.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0004-06222010000400005&lng=en&tlng=en |
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