The DNA damage response in immunotherapy and radiation
Purpose: Deficiencies in DNA damage repair (DDR) and response represent a common alteration in tumors, and exploitation of this feature using therapeutics has become more prominent. Methods and materials: Recent work has highlighted the important interaction between DDR defects, as well as DDR targe...
Main Authors: | Robert M. Samstein, MD, PhD, Nadeem Riaz, MD |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
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Series: | Advances in Radiation Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452109418301490 |
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