Kikuchi-fujimoto disease: A clinical enigma

Background: Kikuchi Fujimoto disease (KFD) is a rare, benign self-limited disease characterized by prolonged regional lymphadenopathy associated with or without systemic signs or symptoms. It is a rare diagnosis in children. Due to the lack of pathognomonic clinical symptoms/signs, KFD poses a signi...

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Main Authors: Sangeeta Priyadarshi Sawant, Alpa S Amin, Prachi R Gaddam, Uma P Chaturvedi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Pediatrics Case Reports
Subjects:
Online Access:http://www.ipcares.org/article.asp?issn=2772-5170;year=2021;volume=1;issue=2;spage=102;epage=104;aulast=Sawant
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author Sangeeta Priyadarshi Sawant
Alpa S Amin
Prachi R Gaddam
Uma P Chaturvedi
author_facet Sangeeta Priyadarshi Sawant
Alpa S Amin
Prachi R Gaddam
Uma P Chaturvedi
author_sort Sangeeta Priyadarshi Sawant
collection DOAJ
description Background: Kikuchi Fujimoto disease (KFD) is a rare, benign self-limited disease characterized by prolonged regional lymphadenopathy associated with or without systemic signs or symptoms. It is a rare diagnosis in children. Due to the lack of pathognomonic clinical symptoms/signs, KFD poses a significant challenge to the clinician. Its diagnosis is confirmed by lymph node biopsy. Clinical Description: A 12.5-year boy presented with chronic cervical lymphadenopathy of 6-week duration, associated with mild-moderate fever, pain, and weight loss. He had raised erythrocyte sedimentation rate, leukopenia, lymphopenia, and thrombocytopenia. Mantoux test was positive. He was managed as a case of tuberculous lymphadenopathy till the lymph node biopsy confirmed the diagnosis of KFD. Management: The child recovered without medications. There has been no recurrence or relapse in 1.5 years of follow-up. Conclusion: This case report highlights the importance of considering the diagnosis of KFD in children presenting with persistent or chronic lymphadenopathy.
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spelling doaj.art-f66ef86bc45f4ae6983bf55891a674d12024-03-25T15:37:18ZengWolters Kluwer Medknow PublicationsIndian Pediatrics Case Reports2772-51702772-51892021-01-011210210410.4103/ipcares.ipcares_77_21Kikuchi-fujimoto disease: A clinical enigmaSangeeta Priyadarshi SawantAlpa S AminPrachi R GaddamUma P ChaturvediBackground: Kikuchi Fujimoto disease (KFD) is a rare, benign self-limited disease characterized by prolonged regional lymphadenopathy associated with or without systemic signs or symptoms. It is a rare diagnosis in children. Due to the lack of pathognomonic clinical symptoms/signs, KFD poses a significant challenge to the clinician. Its diagnosis is confirmed by lymph node biopsy. Clinical Description: A 12.5-year boy presented with chronic cervical lymphadenopathy of 6-week duration, associated with mild-moderate fever, pain, and weight loss. He had raised erythrocyte sedimentation rate, leukopenia, lymphopenia, and thrombocytopenia. Mantoux test was positive. He was managed as a case of tuberculous lymphadenopathy till the lymph node biopsy confirmed the diagnosis of KFD. Management: The child recovered without medications. There has been no recurrence or relapse in 1.5 years of follow-up. Conclusion: This case report highlights the importance of considering the diagnosis of KFD in children presenting with persistent or chronic lymphadenopathy.http://www.ipcares.org/article.asp?issn=2772-5170;year=2021;volume=1;issue=2;spage=102;epage=104;aulast=Sawanthistiocytic necrotizing lymphadenitiskikuchi-fujimoto diseaselymphadenopathy
spellingShingle Sangeeta Priyadarshi Sawant
Alpa S Amin
Prachi R Gaddam
Uma P Chaturvedi
Kikuchi-fujimoto disease: A clinical enigma
Indian Pediatrics Case Reports
histiocytic necrotizing lymphadenitis
kikuchi-fujimoto disease
lymphadenopathy
title Kikuchi-fujimoto disease: A clinical enigma
title_full Kikuchi-fujimoto disease: A clinical enigma
title_fullStr Kikuchi-fujimoto disease: A clinical enigma
title_full_unstemmed Kikuchi-fujimoto disease: A clinical enigma
title_short Kikuchi-fujimoto disease: A clinical enigma
title_sort kikuchi fujimoto disease a clinical enigma
topic histiocytic necrotizing lymphadenitis
kikuchi-fujimoto disease
lymphadenopathy
url http://www.ipcares.org/article.asp?issn=2772-5170;year=2021;volume=1;issue=2;spage=102;epage=104;aulast=Sawant
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